Description

4-Chloro-8-Methoxy-Quinoline-3-Carbonitrile is a high-value, multi-functional quinoline derivative serving as a critical synthetic intermediate. Its unique molecular structure, featuring chloro, methoxy, and nitrile substituents, makes it an essential building block for constructing complex heterocyclic systems. This compound is primarily sought after by pharmaceutical R&D and fine chemical synthesis teams for the development of novel active pharmaceutical ingredients (APIs) and advanced agrochemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly for anti-malarial, anti-cancer, and anti-inflammatory agents.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, leveraging the bioactivity of the quinoline core.
• Material Science Research: Serves as a monomer or precursor for creating organic semiconductors, luminescent materials, and metal-organic frameworks (MOFs).
• Dye and Pigment Industry: Acts as an intermediate for synthesizing specialized quinoline-based dyes and colorants.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological studies in organic synthesis and heterocyclic chemistry.
• Ligand Synthesis: Useful for preparing novel chelating ligands in coordination chemistry and catalysis.

Basic Information

Product Name	4-Chloro-8-Methoxy-Quinoline-3-Carbonitrile
CAS No.	214476-78-5
Molecular Formula	C11H7ClN2O
Molecular Weight	218.64 g/mol
Synonyms	4-Chloro-8-methoxyquinoline-3-carbonitrile; 3-Cyano-4-chloro-8-methoxyquinoline; 8-Methoxy-4-chloroquinoline-3-carbonitrile; Quinoline-3-carbonitrile, 4-chloro-8-methoxy-; 214476-78-5; 4-Chloro-8-methoxy-3-quinolinecarbonitrile
EINECS	Contact for details

Quality Control

Our 4-Chloro-8-Methoxy-Quinoline-3-Carbonitrile is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via FT-IR, NMR, and MS. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, ensuring compliance with your research and production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.