Description

4-Chloro-3-Cyano-7-Ethoxy-6-Nitroquinoline is a high-purity, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. Its unique molecular scaffold, featuring chloro, cyano, ethoxy, and nitro substituents, makes it a versatile precursor for constructing complex pharmacophores and functional materials. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for the development of new active ingredients and high-value intermediates.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the research and development of novel quinoline-based drug candidates, particularly for antimicrobial, anticancer, and anti-inflammatory applications.
• Agrochemical Synthesis: Used as a building block for creating new generations of herbicides, fungicides, and insecticides that leverage the biological activity of the quinoline core.
• Material Science Research: Employed in the synthesis of organic semiconductors, ligands for metal-organic frameworks (MOFs), and fluorescent dyes due to its electron-deficient and modifiable structure.
• Chemical Biology Probes: Acts as a scaffold for developing enzyme inhibitors and molecular probes for biological target identification and validation studies.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects and scale-up processes under cGMP or ISO standards for client-specific molecules.

Basic Information

Product Name	4-Chloro-3-Cyano-7-Ethoxy-6-Nitroquinoline
CAS No.	214476-09-2
Molecular Formula	C₁₂H₈ClN₃O₃
Molecular Weight	277.66 g/mol
Synonyms	4-Chloro-7-ethoxy-6-nitro-3-quinolinecarbonitrile; 7-Ethoxy-4-chloro-6-nitroquinoline-3-carbonitrile; 6-Nitro-7-ethoxy-4-chloroquinoline-3-carbonitrile; 4-Chloro-3-cyano-7-ethoxy-6-nitroquinoline; Quinoline, 4-chloro-3-cyano-7-ethoxy-6-nitro-; 214476-09-2; 4-Chloro-7-ethoxy-6-nitroquinoline-3-carbonitrile
EINECS	Contact for details

Quality Control

Our 4-Chloro-3-Cyano-7-Ethoxy-6-Nitroquinoline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis, to ensure it meets the high standards required for research and development. A detailed Certificate of Analysis (COA) is provided with every shipment, and we support regulatory documentation needs for global supply.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.