Description

(R)-4-(4-Methoxybenzyloxy)-1,2-Butanediol CAS NO 213978-61-1 is a high-purity chiral building block and synthetic intermediate of significant value in advanced organic synthesis. This compound matters for its role as a key precursor in the development of enantiomerically pure pharmaceuticals and fine chemicals, enabling precise stereochemical control. It is primarily needed by research and development chemists, process development scientists, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring specific (R)-configuration stereocenters.
• Asymmetric Synthesis: Used as a starting material or auxiliary in catalytic asymmetric reactions to construct complex molecular architectures.
• Ligand and Catalyst Development: Serves as a backbone for creating novel chiral ligands and organocatalysts used in enantioselective transformations.
• Agrochemical Research: Employed in the research and development of chiral herbicides, fungicides, and plant growth regulators.
• Fine Chemical Production: A valuable intermediate for manufacturing specialty chemicals, flavors, and fragrances where optical purity is essential.
• Academic and Industrial R&D: Utilized in research laboratories for methodological studies and the discovery of new synthetic pathways.

Basic Information

Product Name	(R)-4-(4-Methoxybenzyloxy)-1,2-Butanediol
CAS No.	213978-61-1
Molecular Formula	C12H18O4
Molecular Weight	226.27 g/mol
Synonyms	(R)-4-(p-Methoxybenzyloxy)-1,2-butanediol; (R)-4-[(4-Methoxyphenyl)methoxy]-1,2-butanediol; (R)-PMB-Protected Butanediol; (2R)-4-[(4-Methoxyphenyl)methoxy]butane-1,2-diol; (R)-1,2-Butanediol, 4-[(4-methoxyphenyl)methoxy]-; (R)-4-(4-Methoxybenzyloxy)butane-1,2-diol; (R)-Methoxybenzyloxy Butanediol; (R)-PMB-Butanediol
EINECS	Contact for details

Quality Control

Our (R)-4-(4-Methoxybenzyloxy)-1,2-Butanediol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC for enantiomeric excess (ee) determination, to ensure compliance with high-purity standards for research and development use. Certificates of Analysis (COA) with detailed specifications are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.