Description

1-[(3Ar,8Ar)-Tetrahydro-2,2-Dimethyl-4,4,8,8-Tetraphenyl-1,3-Dioxolo[4,5-E][1,3,2]Dioxaphosphepin-6-Yl]- Piperidine is a sophisticated organophosphorus compound, specifically a chiral phosphite ligand, valued for its role in asymmetric catalysis. This compound matters because it enables highly selective chemical transformations, which are critical for producing enantiomerically pure intermediates in pharmaceutical and fine chemical synthesis. It is primarily needed by research and development chemists and process engineers in the pharmaceutical, agrochemical, and specialty chemical industries who are developing novel synthetic routes requiring precise stereochemical control.

Application

• Asymmetric Hydrogenation Catalyst Ligand: A key component in chiral catalysts for the enantioselective reduction of prochiral olefins, ketones, and imines.
• Pharmaceutical Intermediate Synthesis: Used in the production of enantiomerically pure active pharmaceutical ingredients (APIs) for drugs targeting central nervous system disorders, cardiovascular diseases, and anti-infectives.
• Agrochemical Manufacturing: Employed in the synthesis of chiral herbicides, fungicides, and insecticides to enhance efficacy and reduce environmental impact.
• Fine Chemical Production: Facilitates asymmetric C-C bond formation and other key reactions in the manufacture of flavors, fragrances, and advanced materials.
• Academic & Industrial Research: Serves as a valuable tool for methodology development in organic synthesis and catalysis research.

Basic Information

Product Name	1-[(3Ar,8Ar)-Tetrahydro-2,2-Dimethyl-4,4,8,8-Tetraphenyl-1,3-Dioxolo[4,5-E][1,3,2]Dioxaphosphepin-6-Yl]- Piperidine
CAS No.	213843-95-9
Molecular Formula	C39H38NO4P
Molecular Weight	615.69 g/mol
Synonyms	(3aR,8aR)-6-(Piperidin-1-yl)-2,2-dimethyl-4,4,8,8-tetraphenyltetrahydro-1,3-dioxolo[4,5-e][1,3,2]dioxaphosphepin; (R,R)-DIPAMP Analogue (Phosphite Ligand); Chiral Dioxaphosphepin Ligand; P-Phos Type Ligand; Asymmetric Phosphite Ligand; (3aR,8aR)-Tetrahydro-2,2-dimethyl-4,4,8,8-tetraphenyl-1,3-dioxolo[4,5-e][1,3,2]dioxaphosphepin-6-yl-piperidine
EINECS	Contact for details

Quality Control

Our production of 1-[(3Ar,8Ar)-Tetrahydro-2,2-Dimethyl-4,4,8,8-Tetraphenyl-1,3-Dioxolo[4,5-E][1,3,2]Dioxaphosphepin-6-Yl]- Piperidine adheres to stringent quality management protocols to ensure batch-to-batch consistency and high catalytic performance. Each lot undergoes comprehensive analytical testing, including chiral purity assessment by HPLC, identity confirmation by NMR and IR spectroscopy, and quantification of key impurities. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation and maintain catalytic activity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.