Description

(S)-tert-Butyl 2-Amino-2-Cyclohexylacetate Hydrochloride is a high-purity chiral building block essential for the synthesis of complex pharmaceutical intermediates. Its value lies in providing a stereochemically defined cyclohexylglycine derivative, crucial for developing active pharmaceutical ingredients (APIs) with specific biological activity. This compound is primarily needed by research institutions and manufacturers in the pharmaceutical and agrochemical industries for drug discovery and process development.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of peptide-mimetic drugs and protease inhibitors.
• Agrochemical Research: Used in developing novel chiral active ingredients for crop protection.
• Asymmetric Synthesis: Serves as a valuable starting material or auxiliary in stereoselective chemical transformations.
• API Development: Critical for constructing the core scaffold of potential drug candidates targeting neurological and metabolic diseases.
• Custom Synthesis: A building block for contract research and manufacturing organizations (CROs/CMOs) producing bespoke compounds for clients.

Basic Information

Product Name	(S)-tert-Butyl 2-Amino-2-Cyclohexylacetate Hydrochloride
CAS No.	213475-52-6
Molecular Formula	C₁₂H₂₄ClNO₂
Molecular Weight	249.78 g/mol
Synonyms	(S)-2-Amino-2-cyclohexylacetic acid tert-butyl ester hydrochloride; (S)-tert-Butyl 2-amino-2-cyclohexylacetate HCl; (S)-Cyclohexylglycine tert-butyl ester hydrochloride; (S)-2-(tert-Butoxycarbonylamino)-2-cyclohexylacetic acid; (S)-Boc-Cyclohexylglycine-OH (tert-butyl ester form); L-Cyclohexylglycine tert-butyl ester hydrochloride; (S)-α-Aminocyclohexaneacetic acid 1,1-dimethylethyl ester hydrochloride
EINECS	Contact for details

Quality Control

Our (S)-tert-Butyl 2-Amino-2-Cyclohexylacetate Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with high-grade standards suitable for research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.