Description

(-)-1,2-Bis((2S,5S)-2,5-Dimethylphospholano)Ethane(Cyclooctadiene)Rhodium(I)Trifluoromethanesulfonate,98+%(S,S)-Me-Bpe-Rh CAS NO 213343-69-2 is a high-purity, chiral bisphosphine ligand-rhodium complex, specifically designed as a highly efficient and enantioselective catalyst for asymmetric hydrogenation and other transition metal-catalyzed reactions. Its value lies in providing exceptional stereochemical control, enabling the production of single-enantiomer intermediates critical for advanced pharmaceuticals and fine chemicals. This product is essential for R&D scientists and process chemists in the pharmaceutical, agrochemical, and specialty chemical industries who require reliable, high-performance chiral catalysts to develop novel synthetic routes and optimize manufacturing processes.

Application

• Asymmetric Hydrogenation Catalyst: For the enantioselective reduction of prochiral olefins, ketones, and imines to produce chiral alcohols and amines.
• Pharmaceutical Intermediate Synthesis: Key for manufacturing single-enantiomer active pharmaceutical ingredients (APIs), such as β-amino acids and other chiral building blocks.
• Agrochemical Production: Used in the synthesis of enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Fine Chemical and Fragrance Manufacturing: Enables the production of high-value chiral compounds for flavors, fragrances, and advanced materials.
• Academic and Industrial R&D: A valuable tool for method development and exploring new catalytic asymmetric transformations in organic synthesis.
• Process Chemistry Optimization: Employed to scale up and improve the efficiency and selectivity of existing catalytic processes.

Basic Information

Item	Details
Product Name	(-)-1,2-Bis((2S,5S)-2,5-Dimethylphospholano)Ethane(Cyclooctadiene)Rhodium(I)Trifluoromethanesulfonate
CAS No.	213343-69-2
Molecular Formula	C₂₂H₄₀F₃O₃P₂RhS
Molecular Weight	618.46 g/mol
Synonyms	(S,S)-Me-BPE-Rh(COD)OTf; (S,S)-Me-BPE-Rhodium(I) Triflate; (S,S)-2,2'-Dimethyl-1,1'-bis(2,5-dimethylphospholano)ethane(cyclooctadiene)rhodium(I) trifluoromethanesulfonate; (S,S)-Me-DuPhos-Rhodium(COD) Triflate Analog; Rh-((S,S)-Me-BPE)(COD)OTf; (S,S)-1,2-Bis(2,5-dimethylphospholano)ethane(1,5-cyclooctadiene)rhodium(I) trifluoromethanesulfonate; (S,S)-Me-BPE Rh(COD)OTf Catalyst
EINECS	Contact for details

Quality Control

Our 98+% purity grade of this chiral rhodium catalyst is produced under strict quality-controlled conditions to ensure batch-to-batch consistency and optimal catalytic performance. Each lot undergoes comprehensive analysis, including chiral purity assessment by HPLC, elemental analysis, and spectroscopic identification (NMR, IR). Certificates of Analysis (COA) detailing all specifications are provided to guarantee the material meets the stringent requirements for advanced asymmetric synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) at 2-8°C in a freezer. This compound is easily oxidized and moisture-sensitive; prolonged exposure to air or ambient conditions should be avoided to maintain catalytic activity and purity.

Specification

Item	Specification
Appearance	Orange to red-brown solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Rhodium Content	~16.6% (Theoretical)
Solubility	Soluble in dichloromethane, chloroform, THF

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.