Description

1,2-Bis((2S,5S)-2,5-Di-I-Propylphospholano)Ethane(Cyclooctadiene)Rhodium(I) Tetrafluoroborate is a highly specialized, chiral organometallic catalyst of significant commercial importance. This compound, with CAS number 213343-67-0, is prized for its exceptional enantioselectivity and catalytic activity in asymmetric hydrogenation reactions. It is a critical reagent for pharmaceutical, agrochemical, and fine chemical manufacturers requiring the production of single-enantiomer intermediates and active ingredients.

Application

• Asymmetric Hydrogenation Catalyst: Primary application for the enantioselective reduction of prochiral olefins, enamides, and ketones in pharmaceutical synthesis.
• Pharmaceutical Intermediate Production: Key for manufacturing chiral active pharmaceutical ingredients (APIs), including β-amino acids and other complex molecules.
• Agrochemical Synthesis: Used in the production of enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Fine Chemical and Fragrance Manufacturing: Enables the synthesis of high-value chiral flavor and fragrance compounds.
• Academic and Industrial R&D: A valuable tool for method development and discovery chemistry in asymmetric catalysis.
• Process Chemistry Optimization: Employed for scaling up efficient and selective catalytic processes in pilot plants and commercial production.

Basic Information

Product Name	1,2-Bis((2S,5S)-2,5-Di-I-Propylphospholano)Ethane(Cyclooctadiene)Rhodium(I) Tetrafluoroborate
CAS No.	213343-67-0
Molecular Formula	C30H56BF4P2Rh
Molecular Weight	668.43 g/mol
Synonyms	(S,S)-Et-DuPhos Rhodium(I) Tetrafluoroborate COD Complex; [Rh((S,S)-Et-DuPhos)(COD)]BF4; (1,5-Cyclooctadiene)[(2S,5S)-2,5-Diethylphospholano]ethane Rhodium(I) Tetrafluoroborate; Rh-(S,S)-Et-DuPhos Catalyst; DuPhos Rhodium Catalyst; Asymmetric Hydrogenation Catalyst Rh-Et-DuPhos; (S,S)-1,2-Bis(2,5-Diethylphospholano)ethane(1,5-cyclooctadiene)rhodium(I) Tetrafluoroborate
EINECS	Contact for details

Quality Control

Our high-value chiral catalysts are produced and handled under strict inert atmosphere conditions to guarantee activity and purity. Each batch undergoes comprehensive analytical characterization, including NMR, HPLC, and elemental analysis, to confirm chemical identity, enantiomeric purity, and catalytic performance. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality parameters.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) at 2-8°C in a freezer. This compound is hygroscopic (moisture-sensitive) and easily oxidized; exposure to air, moisture, or elevated temperatures will degrade the catalyst and reduce its efficacy.

Specification

Item	Specification
Appearance	Orange to red-brown crystalline solid or powder
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Rhodium Content	15.0 - 16.0 %
Solubility	Soluble in dichloromethane, acetone, THF; sparingly soluble in alcohols

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.