Description

(+)-1,2-Bis((2S,5S)-2,5-Diethylphospholano)Benzene(Cyclooctadiene)Rhodium(L)Tetrafluoroborate CAS NO 213343-64-7 is a highly specialized, chiral organometallic catalyst complex, specifically a rhodium-based bisphosphine ligand system. Its primary value lies in enabling highly enantioselective hydrogenation and other asymmetric transformations, which are critical for producing single-isomer active pharmaceutical ingredients (APIs) and fine chemicals. This product is essential for R&D chemists and process engineers in the pharmaceutical, agrochemical, and advanced materials sectors who require precise stereochemical control.

Application

• Asymmetric Hydrogenation Catalyst: For the enantioselective synthesis of chiral amino acids, amines, alcohols, and other pharmaceutical intermediates.
• Pharmaceutical API Manufacturing: Key catalyst in the production of single-enantiomer drugs, including cardiovascular, central nervous system (CNS), and antiviral agents.
• Agrochemical Synthesis: Used in the creation of enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Fine Chemical Production: Enables the synthesis of complex, high-value chiral molecules for flavors, fragrances, and electronic chemicals.
• Academic & Industrial R&D: A vital tool for method development and exploring new asymmetric catalytic cycles in organic synthesis.
• Process Chemistry Optimization: Employed for scaling up efficient and selective catalytic processes from laboratory to pilot plant and production scale.

Basic Information

Item	Detail
Product Name	(+)-1,2-Bis((2S,5S)-2,5-Diethylphospholano)Benzene(Cyclooctadiene)Rhodium(L)Tetrafluoroborate
CAS No.	213343-64-7
Molecular Formula	C36H56BF4P2Rh
Molecular Weight	720.47 g/mol
Synonyms	(S,S)-Et-DuPhos Rhodium(I) Tetrafluoroborate COD Complex; [Rh((S,S)-Et-DuPhos)(COD)]BF4; (S,S)-1,2-Bis(2,5-Diethylphospholano)benzene(1,5-cyclooctadiene)rhodium(I) tetrafluoroborate; Rh-(S,S)-Et-DuPhos Catalyst; (S,S)-Et-DuPhos-Rh(COD)BF4; DuPhos Rhodium Catalyst; Chiral Rhodium Bisphosphine Complex
EINECS	Contact for details

Quality Control

Every batch of our chiral catalyst is produced and analyzed under strict inert atmosphere conditions to ensure activity and enantiomeric purity. We employ advanced analytical techniques including NMR, HPLC, and elemental analysis to verify chemical identity, purity, and the absence of deleterious impurities. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) at 2-8°C (refrigerated) or as specified on the label. Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed in a dry environment and allowed to equilibrate to room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	Orange to red-brown crystalline solid or powder
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Rhodium Content	Contact for details
Solubility	Soluble in dichloromethane, tetrahydrofuran; slightly soluble in toluene

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.