Description

S-3-(1-Naphthalenyloxy)-Pyrrolidine Hydrochloride is a high-purity chiral building block and intermediate of significant interest in advanced organic synthesis. Its value lies in its defined stereochemistry and functionalized pyrrolidine core, which are crucial for constructing complex molecules with specific biological activity. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and other fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of potential therapeutic agents, particularly for central nervous system (CNS) targets.
• Agrochemical Synthesis: Used in the creation of advanced, enantiomerically pure crop protection agents and herbicides.
• Asymmetric Catalysis Ligand Precursor: Serves as a starting material for synthesizing specialized ligands used in chiral catalysis.
• Academic & Industrial R&D: Employed in medicinal chemistry programs for structure-activity relationship (SAR) studies and hit-to-lead optimization.
• Fine Chemical Production: Integral in multi-step synthetic routes for producing other high-value, specialty chemicals.

Basic Information

Product Name	S-3-(1-Naphthalenyloxy)-Pyrrolidine Hydrochloride
CAS No.	213007-99-9
Molecular Formula	C₁₄H₁₆ClNO
Molecular Weight	249.74 g/mol
Synonyms	(S)-3-(Naphthalen-1-yloxy)pyrrolidine hydrochloride; (S)-3-(1-Naphthyloxy)pyrrolidine HCl; 1-Naphthalenol, 3-(S)-3-pyrrolidinyl ether, hydrochloride; S-3-(1-Naphthoxy)pyrrolidine hydrochloride; (3S)-3-(Naphthalen-1-yloxy)pyrrolidine hydrochloride; Pyrrolidine, 3-[(1-naphthalenyl)oxy]-, hydrochloride, (3S)-; UNII-9J3T9K1K4F
EINECS	Contact for details

Quality Control

Our S-3-(1-Naphthalenyloxy)-Pyrrolidine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research and development applications. A detailed Certificate of Analysis (COA) providing batch-specific data for identity, purity, and related substances is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.