Description

Diendo-3-Benzoylbicyclo[2.2.1]heptane-2-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate characterized by its complex, rigid bicyclic structure. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting central nervous system and inflammatory pathways. It is essential for research and development chemists, process chemists, and manufacturers in the pharmaceutical and fine chemical industries seeking to develop new therapeutic entities with high stereochemical control.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and production of novel drug candidates, especially in neurology and immunology.
• Organic Synthesis Building Block: Utilized in complex organic transformations, including Diels-Alder reactions and further functionalization, due to its strained bicyclic framework.
• Asymmetric Catalysis Research: Serves as a substrate or ligand precursor in the development of new asymmetric catalytic processes.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to explore new chemical spaces for drug discovery.
• Reference Standard: Employed as an analytical standard for quality control and method development in API manufacturing.

Basic Information

Item	Details
Product Name	Diendo-3-Benzoylbicyclo[2.2.1]heptane-2-Carboxylic Acid
CAS No.	212757-12-5
Molecular Formula	C15H16O3
Molecular Weight	244.29 g/mol
Synonyms	3-Benzoylbicyclo[2.2.1]heptane-2-carboxylic acid, endo isomer; Di-endo-3-Benzoylbicyclo[2.2.1]heptane-2-carboxylic Acid; Bicyclo[2.2.1]heptane-2-carboxylic acid, 3-benzoyl-, endo-; (1R,2S,3R,4S)-3-Benzoylbicyclo[2.2.1]heptane-2-carboxylic acid; endo-3-Benzoylnorbornane-2-carboxylic Acid
EINECS	Contact for details

Quality Control

Our Diendo-3-Benzoylbicyclo[2.2.1]heptane-2-Carboxylic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and chiral purity analysis, to ensure it meets the high standards required for pharmaceutical R&D and production. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and organic solvents. The container must be kept tightly closed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 99.0%
Chiral Purity	≥ 99.0% ee (endo isomer)
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.