Description

6-(Trifluoromethoxy)Quinoline is a high-value fluorinated heterocyclic building block, distinguished by its trifluoromethoxy substituent which imparts unique electronic properties and metabolic stability. This compound is essential for advanced research and development in life sciences, enabling the synthesis of novel molecules with enhanced biological activity and physicochemical profiles. It is primarily sought after by pharmaceutical and agrochemical R&D teams for creating next-generation active ingredients, as well as by material scientists exploring specialty polymers and electronic materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Active Ingredient Precursor: Used in the synthesis of advanced herbicides and pesticides with improved efficacy and environmental profiles.
• Material Science Research: Serves as a monomer or functional additive in the development of specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Biology & Probe Development: Employed in the design of fluorescent probes and molecular tags due to the quinoline scaffold's photophysical properties.
• Catalyst Ligand Synthesis: The nitrogen heterocycle can be utilized to create novel ligands for transition metal catalysis.
• Academic & Contract Research: A valuable reagent for methodological studies in organic synthesis, particularly in cross-coupling and fluorination chemistry.

Basic Information

Product Name	6-(Trifluoromethoxy)Quinoline
CAS No.	212695-45-9
Molecular Formula	C₁₀H₆F₃NO
Molecular Weight	213.16 g/mol
Synonyms	6-(Trifluoromethoxy)quinoline; Quinoline, 6-(trifluoromethoxy)-; 6-Trifluoromethoxyquinoline; 6-(Trifluoromethoxy)chinolin; 212695-45-9; 6-TFMQ
EINECS	Contact for details

Quality Control

Every batch of 6-(Trifluoromethoxy)Quinoline is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the compound meets the high-purity standards required for research and development applications. A detailed Certificate of Analysis (COA), including results from HPLC, NMR, and GC-MS, is supplied with each shipment to guarantee identity, purity, and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Melting Point	Contact for details
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.