Description

(1R,2R)-N',N'-Bis(Phenylmethyl)-,1,2-Cyclohexanediamine Hydrochloride (1:2) is a high-purity chiral diamine salt, a critical building block in asymmetric synthesis and pharmaceutical development. Its value lies in its role as a versatile ligand and resolving agent, enabling the production of enantiomerically pure compounds essential for advanced therapeutics and fine chemicals. This product is primarily needed by research institutions, pharmaceutical manufacturers, and fine chemical companies engaged in the synthesis of chiral active pharmaceutical ingredients (APIs), catalysts, and specialty materials.

Application

• As a chiral ligand in asymmetric catalysis for the synthesis of enantiomerically pure pharmaceuticals.
• As a resolving agent for the separation of racemic mixtures in fine chemical production.
• In the research and development of novel organocatalysts and metal-complex catalysts.
• As a key intermediate in the synthesis of complex molecules for medicinal chemistry studies.
• For the preparation of chiral stationary phases used in analytical chromatography.
• In the development of specialty polymers and materials requiring chiral induction.

Basic Information

Product Name	(1R,2R)-N',N'-Bis(Phenylmethyl)-,1,2-Cyclohexanediamine Hydrochloride (1:2)
CAS No.	212611-88-6
Molecular Formula	C20H28N2·2HCl
Molecular Weight	377.37 g/mol (free base: 296.45 g/mol)
Synonyms	(1R,2R)-(-)-1,2-Bis(benzylamino)cyclohexane Dihydrochloride; (1R,2R)-1,2-Dibenzylaminocyclohexane Dihydrochloride; (1R,2R)-N,N'-Dibenzylcyclohexane-1,2-diamine Dihydrochloride; (1R,2R)-(-)-1,2-Diaminocyclohexane N,N'-Dibenzyl Dihydrochloride; (R,R)-DACH-Benzyl Dihydrochloride; (R,R)-1,2-Bis(benzylamino)cyclohexane 2HCl; (1R,2R)-DACH-(Bn)2·2HCl
EINECS	Contact for details

Quality Control

Our (1R,2R)-N',N'-Bis(Phenylmethyl)-,1,2-Cyclohexanediamine Hydrochloride (1:2) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with exacting standards for research and pharmaceutical applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and chiral excess is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.