Description

(1S,2R)-1-(2-(Hydroxy-3,5-Di-tert-Butyl (CAS 212378-89-7) is a high-purity, chiral chemical intermediate of significant importance in advanced organic synthesis. Its value lies in its defined stereochemistry, which is critical for producing enantiomerically pure compounds with specific biological activity. This product is essential for research and development laboratories and production facilities in the pharmaceutical and agrochemical sectors, where it serves as a key building block for active ingredients.

Application

• Pharmaceutical Intermediate: A crucial chiral synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in cardiovascular and central nervous system (CNS) drug candidates.
• Agrochemical Synthesis: Used in the production of enantiomerically pure herbicides, fungicides, and plant growth regulators, where specific stereochemistry enhances efficacy and reduces environmental impact.
• Asymmetric Catalysis: Employed as a ligand precursor or a chiral auxiliary in catalytic processes to induce stereoselectivity in chemical transformations.
• Fine Chemical Production: Serves as a specialized building block for high-value flavors, fragrances, and advanced materials requiring precise molecular architecture.
• Academic & Industrial R&D: A valuable compound for methodological development in organic chemistry and for exploring new synthetic pathways in process chemistry.

Basic Information

Product Name	(1S,2R)-1-(2-(Hydroxy-3,5-Di-tert-Butyl
CAS No.	212378-89-7
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	(1S,2R)-1-[2-Hydroxy-3,5-di-tert-butylphenyl]ethan-1-ol; (1S,2R)-1-(2-Hydroxy-3,5-di-tert-butylphenyl)ethanol; 1-(2-Hydroxy-3,5-di-tert-butylphenyl)ethanol (enantiomer); Chiral DTBPE; (1S,2R)-DTBPE; 212378-89-7; Light-sensitive phenolic chiral alcohol.
EINECS	Contact for details

Quality Control

Our (1S,2R)-1-(2-(Hydroxy-3,5-Di-tert-Butyl is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including chiral HPLC for enantiomeric excess (ee) verification and purity assessment. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and specific impurities is provided with each shipment to ensure compliance with your project specifications and GMP guidelines where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at controlled room temperature (15-25°C) in a cool, dry, and well-ventilated place. Due to its sensitivity to oxidation, minimize headspace and exposure to air after opening.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.