Description

Benzocaine Methanethiosulfonate is a specialized chemical reagent that combines the anesthetic benzocaine moiety with a methanethiosulfonate functional group. This compound is of significant value in biochemical and pharmaceutical research, particularly for site-directed spin labeling and covalent modification of cysteine residues in proteins. It is primarily sought by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in advanced proteomics, structural biology, and the development of novel therapeutic agents.

Application

• Site-Directed Spin Labeling (SDSL): A key reagent for introducing spin labels onto specific cysteine sites in proteins for Electron Paramagnetic Resonance (EPR) spectroscopy studies.
• Protein Structure & Dynamics Research: Used to probe protein conformational changes, folding, and interactions by covalently attaching reporter groups.
• Bioconjugation & Protein Engineering: Facilitates the creation of chemically modified proteins for diagnostic, therapeutic, or material science applications.
• Pharmaceutical Intermediate: Serves as a building block in the synthesis of more complex molecules with potential pharmacological activity.
• Biochemical Probe Development: Employed in the design and synthesis of probes for studying enzyme mechanisms and active sites.

Basic Information

Product Name	Benzocaine Methanethiosulfonate
CAS No.	212207-24-4
Molecular Formula	C10H13NO4S2
Molecular Weight	275.34 g/mol
Synonyms	Ethyl 4-[(Methanesulfonylthio)carbonyl]aminobenzoate; Benzocaine MTS; MTSL-Benzocaine derivative; 4-[(Methylsulfonyl)thio]carbonylaminobenzoic Acid Ethyl Ester; Benzocaine-S-Methanethiosulfonate; Protein Spin Labeling Reagent; Cysteine-specific Modification Reagent; Benzocaine Thiol-reactive Reagent
EINECS	Contact for details

Quality Control

Our Benzocaine Methanethiosulfonate is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency, suitable for sensitive research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP guidelines where applicable to support our clients in pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is light-sensitive (store away from light). For long-term storage, consider keeping the container under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.