Description

Quinoline, 6-Ethoxy-1,2,3,4-Tetrahydro-2,2,4-Trimethyl-, (4S)- (9Ci) is a high-value, stereochemically defined tetrahydroquinoline derivative. This compound serves as a critical chiral building block and advanced pharmaceutical intermediate for the synthesis of complex bioactive molecules. It is primarily utilized by pharmaceutical R&D and fine chemical synthesis sectors requiring high-purity, optically active intermediates.

Application

• Pharmaceutical Intermediate: Key chiral precursor in the synthesis of potential drug candidates targeting central nervous system (CNS) disorders and other therapeutic areas.
• Asymmetric Synthesis: Utilized as a chiral auxiliary or scaffold in catalytic asymmetric reactions to induce stereoselectivity.
• Agrochemical Research: Building block for developing novel, optically active crop protection agents and pesticides.
• Material Science: Potential monomer or additive for creating specialized polymers with unique optical or electronic properties.
• Academic & Industrial R&D: Serves as a standard or starting material for methodological development in organic and medicinal chemistry.

Basic Information

Product Name	Quinoline, 6-Ethoxy-1,2,3,4-Tetrahydro-2,2,4-Trimethyl-, (4S)- (9Ci)
CAS No.	212186-69-1
Molecular Formula	C14H21NO
Molecular Weight	219.32 g/mol
Synonyms	(4S)-6-Ethoxy-2,2,4-trimethyl-1,2,3,4-tetrahydroquinoline; (S)-6-Ethoxy-2,2,4-trimethyl-1,2,3,4-tetrahydroquinoline; 6-Ethoxy-2,2,4-trimethyl-1,2,3,4-tetrahydroquinoline (S-isomer); 1,2,3,4-Tetrahydro-6-ethoxy-2,2,4-trimethylquinoline, (S)-; ETMQ (S-form); Chiral Tetrahydroquinoline Derivative
EINECS	Contact for details

Quality Control

Our production of this chiral intermediate adheres to strict quality protocols to ensure batch-to-batch consistency and high optical purity. Quality is verified through advanced analytical techniques including Chiral HPLC, NMR, and GC-MS. A comprehensive Certificate of Analysis (COA) detailing identity, purity (assay), chiral excess, and impurity profile is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents. For long-term storage under an inert atmosphere (e.g., nitrogen or argon), please contact our technical team.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (Assay by GC/HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.