Description

2-(Methylsulfinyl)Quinazolin-4(3H)-One is a high-purity, advanced pharmaceutical intermediate characterized by its unique sulfinyl-substituted quinazolinone core structure. This compound is of significant commercial interest for its role in the synthesis of novel bioactive molecules targeting various therapeutic areas. It is primarily utilized by research institutions and pharmaceutical development companies engaged in medicinal chemistry and drug discovery programs.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of potential kinase inhibitors and other small-molecule drug candidates.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to explore new chemical entities for oncology, inflammation, and central nervous system (CNS) disorders.
• Chemical Biology Probes: Employed in the development of tool compounds for studying enzyme function and cellular signaling pathways.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and scale-up of novel active pharmaceutical ingredients (APIs).
• Academic Research: Utilized in university and institutional labs for fundamental research in heterocyclic chemistry and organic synthesis methodologies.

Basic Information

Product Name	2-(Methylsulfinyl)Quinazolin-4(3H)-One
CAS No.	212143-48-1
Molecular Formula	C9H8N2O2S
Molecular Weight	208.24 g/mol
Synonyms	2-(Methylsulfinyl)-4(3H)-quinazolinone; 2-Methylsulfinylquinazolin-4(3H)-one; Quinazolin-4(3H)-one, 2-(methylsulfinyl)-; 4(3H)-Quinazolinone, 2-(methylsulfinyl)-; 2-Methanesulfinylquinazolin-4(3H)-one; 2-(Methylsulfinyl)-3,4-dihydroquinazolin-4-one; 212143-48-1
EINECS	Contact for details

Quality Control

Our 2-(Methylsulfinyl)Quinazolin-4(3H)-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting key specifications such as assay, related substances, and residual solvents.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.