Description

Dichloro[(R)-(+)-2,2'-Bis(Diphenylphosphino)-1,1'-Binaphthyl][(1R,2R)-(+)-1,2-Diphenylethylenediamine]Ruthenium (II) is a highly specialized, chiral ruthenium complex that serves as a premier asymmetric hydrogenation catalyst. This compound matters because it enables the efficient and selective synthesis of single-enantiomer intermediates, which are critical for the production of high-value pharmaceuticals and fine chemicals. It is essential for R&D chemists and process engineers in the pharmaceutical, agrochemical, and advanced materials sectors who require precise stereochemical control. The product is supplied with a CAS number of 212143-23-2.

Application

• Asymmetric Hydrogenation Catalyst: For the enantioselective reduction of functionalized olefins, ketones, and imines in pharmaceutical intermediate synthesis.
• Chiral Ligand Complex: As a pre-formed catalyst for research into novel asymmetric transformations beyond hydrogenation.
• Pharmaceutical Manufacturing: Key catalyst in the production of active pharmaceutical ingredients (APIs) requiring high enantiomeric purity, such as certain antibiotics, antivirals, and cardiovascular drugs.
• Fine Chemical Synthesis: Used in the pilot and commercial-scale manufacture of specialty chemicals, flavors, and fragrances where chirality is a defining property.
• Academic & Industrial R&D: A valuable tool for method development and exploring new catalytic pathways in organic synthesis laboratories.
• Agrochemical Intermediate Production: For creating enantiomerically pure herbicides, fungicides, and plant growth regulators.

Basic Information

Product Name	Dichloro[(R)-(+)-2,2'-Bis(Diphenylphosphino)-1,1'-Binaphthyl][(1R,2R)-(+)-1,2-Diphenylethylenediamine]Ruthenium (II)
CAS No.	212143-23-2
Molecular Formula	C52H44Cl2N2P2Ru
Molecular Weight	932.85 g/mol
Synonyms	RuCl2[(R)-BINAP][(R,R)-DPEN]; (R,R)-Ru-BINAP-DPEN; Dichloro[(R)-2,2'-bis(diphenylphosphino)-1,1'-binaphthyl][(1R,2R)-1,2-diphenylethylenediamine]ruthenium; Noyori-Ikariya Catalyst; [RuCl2((R)-binap)((R,R)-dpen)]; Asymmetric Hydrogenation Catalyst (Ru-BINAP-DPEN); Ruthenium(II) (R)-BINAP (R,R)-DPEN complex
EINECS	Contact for details

Quality Control

Every batch of our chiral ruthenium catalyst is produced and tested under strict quality management protocols to ensure consistent high performance. We provide comprehensive Certificates of Analysis (COA) detailing critical parameters such as purity, chiral purity, and metal content. Our quality systems are designed to support cGMP and ISO standards for customers in regulated industries, ensuring traceability and reliability for your most sensitive synthetic processes.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) at 2-8°C to maintain stability and prevent decomposition. This material is easily oxidized and light-sensitive; prolonged exposure to air, moisture, or ambient light should be avoided to preserve catalytic activity.

Specification

Item	Specification
Appearance	Orange to red-brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% ee
Ruthenium Content	10.5 - 11.5 %
Solubility	Soluble in dichloromethane, toluene; slightly soluble in methanol

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.