Description

(R)-1-(Diphenylphosphino)-2-[(S)-4-Isopropyl-2-Oxazolin-2-Yl]Ferrocene Triphenylphosphine Ruthenium(II) Chloride Complex is a highly specialized, chiral ruthenium-based catalyst complex. This compound is valued for its exceptional stereoselectivity and catalytic efficiency in asymmetric synthesis, enabling the production of high-value enantiomerically pure intermediates. It is primarily sought by R&D laboratories and production facilities in the pharmaceutical and fine chemical industries for advanced catalytic transformations.

Application

• Asymmetric Hydrogenation: A key catalyst for the enantioselective reduction of prochiral olefins, ketones, and imines, critical for synthesizing chiral pharmaceutical building blocks.
• Pharmaceutical Intermediate Synthesis: Used in the production of active pharmaceutical ingredients (APIs) requiring high enantiomeric purity, such as certain antibiotics, antivirals, and cardiovascular drugs.
• Fine Chemical Manufacturing: Enables the synthesis of complex, chiral molecules for agrochemicals, flavors, and fragrances.
• Academic and Industrial Research: Serves as a benchmark catalyst in methodological development for new asymmetric catalytic processes.
• Catalyst Ligand Precursor: The ferrocenyl phosphine-oxazoline ligand framework can be studied or modified for developing next-generation chiral catalysts.

Basic Information

Product Name	(R)-1-(Diphenylphosphino)-2-[(S)-4-Isopropyl-2-Oxazolin-2-Yl]Ferrocene Triphenylphosphine Ruthenium(II) Chloride Complex
CAS No.	212133-11-4
Molecular Formula	C45H42ClFeNOP2Ru
Molecular Weight	849.15 g/mol
Synonyms	RuCl[(R)-Phosferrox][PPh3]; (R)-1-(Diphenylphosphino)-2-[(S)-4-isopropyl-2-oxazolinyl]ferrocene triphenylphosphine ruthenium dichloride; [RuCl((R)-Phosferrox)(PPh3)]Cl; Ruthenium(II) chloride complex with (R)-1-(diphenylphosphino)-2-[(S)-4-isopropyl-2-oxazolin-2-yl]ferrocene and triphenylphosphine; Josiphos-type Ru catalyst; Chiral ruthenium Josiphos complex; Asymmetric hydrogenation catalyst Ru-Phosferrox.
EINECS	Contact for details

Quality Control

Every batch of our (R)-1-(Diphenylphosphino)-2-[(S)-4-Isopropyl-2-Oxazolin-2-Yl]Ferrocene Triphenylphosphine Ruthenium(II) Chloride Complex is manufactured and handled under strict quality protocols. Our products undergo rigorous analytical testing, including NMR, HPLC, and elemental analysis, to ensure identity, purity, and catalytic performance. A comprehensive Certificate of Analysis (COA) detailing batch-specific results is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., argon or nitrogen) at 2-8°C to maintain stability and prevent decomposition. The compound is easily oxidized and moisture-sensitive; ensure the container is sealed immediately after use and stored in a cool, dry, well-ventilated place.

Specification

Item	Specification
Appearance	Orange to red-brown crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Chiral Purity	≥ 99.0% ee
Elemental Analysis	Within theoretical ± 0.4%
Solubility	Soluble in dichloromethane, toluene; slightly soluble in THF

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.