Description

Tri-n-Butyl[(2-Methyl-1,3-Thiazol-4-Yl)Methyl]Phosphonium Chloride is a specialized organophosphorus compound featuring a thiazole moiety, serving as a versatile intermediate and catalyst in advanced organic synthesis. Its unique structure makes it a valuable reagent for constructing complex molecules, particularly in the development of pharmaceuticals and agrochemicals. This high-purity chemical is essential for research and production chemists in fine chemical, pharmaceutical, and life science industries seeking to drive innovation in their synthetic processes.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing heterocyclic structures.
• Agrochemical Synthesis: Used in the research and production of novel pesticides, herbicides, and fungicides that require specific thiazole-based active components.
• Ligand & Catalyst Precursor: Serves as a precursor for phosphonium-based ligands and phase-transfer catalysts used in asymmetric synthesis and other specialized reactions.
• Material Science Research: Employed in the development of advanced materials, including ionic liquids and functional polymers with tailored properties.
• Organic Synthesis Reagent: Facilitates various carbon-carbon and carbon-heteroatom bond-forming reactions as a specialized phosphonium salt.
• Life Science & Biochemical Research: Used as a tool compound in medicinal chemistry for structure-activity relationship (SAR) studies and probe development.

Basic Information

Product Name	Tri-n-Butyl[(2-Methyl-1,3-Thiazol-4-Yl)Methyl]Phosphonium Chloride
CAS No.	211919-65-2
Molecular Formula	C₁₇H₃₁ClNPS
Molecular Weight	347.92 g/mol
Synonyms	Tributyl(2-methyl-4-thiazolylmethyl)phosphonium chloride; (2-Methyl-4-thiazolylmethyl)tributylphosphonium chloride; Tributyl[(2-methyl-1,3-thiazol-4-yl)methyl]phosphonium chloride; Phosphonium, tributyl[(2-methyl-4-thiazolyl)methyl]-, chloride; 4-[(Tributylphosphonio)methyl]-2-methylthiazole chloride
EINECS	Contact for details

Quality Control

Our Tri-n-Butyl[(2-Methyl-1,3-Thiazol-4-Yl)Methyl]Phosphonium Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all relevant specifications to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere such as nitrogen or argon to prevent degradation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.