Description

n-Cyclopropyl-n-Tetrahydro-2H-Pyran-4-Ylamine is a versatile and high-value amine derivative featuring both cyclopropyl and tetrahydropyranyl functional groups. This unique heterocyclic structure makes it a critical pharmaceutical intermediate and a valuable building block in advanced organic synthesis. It is primarily sought after by research and development teams in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures. The compound's bifunctional nature allows for selective modifications, enabling the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and antiviral drug discovery programs.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, leveraging the biological activity of the cyclopropylamine moiety.
• Ligand and Catalyst Development: Serves as a precursor for creating chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the development of advanced polymers and functional materials requiring specific amine functionalities.
• Chemical Biology Probes: Utilized as a scaffold for designing molecular probes and inhibitors to study enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses serving the pharmaceutical and biotechnology sectors.

Basic Information

Product Name	n-Cyclopropyl-n-Tetrahydro-2H-Pyran-4-Ylamine
CAS No.	211814-16-3
Molecular Formula	C8H15NO
Molecular Weight	141.21 g/mol
Synonyms	4-(Cyclopropylamino)tetrahydro-2H-pyran; N-Cyclopropyltetrahydro-2H-pyran-4-amine; Tetrahydro-2H-pyran-4-amine, N-cyclopropyl-; 4-Aminotetrahydropyran, N-cyclopropyl derivative; CPTHPA; Cyclopropyl(tetrahydro-2H-pyran-4-yl)amine
EINECS	Contact for details

Quality Control

Every batch of n-Cyclopropyl-n-Tetrahydro-2H-Pyran-4-Ylamine is produced under strict quality management systems. We employ advanced analytical techniques including HPLC, GC, NMR, and MS to ensure identity, purity, and consistency. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) with detailed chromatographic data are available upon request, providing full traceability and batch-to-batch reliability for your critical R&D and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.