Description

Methyl (1S,2R,3R,8S)-4-Formylcubane-1-Carboxylate is a highly specialized and synthetically challenging cubane derivative, representing a pinnacle of structural chemistry and advanced organic synthesis. This compound is valued for its unique three-dimensional cage-like geometry, which imparts exceptional thermal stability and strain energy, making it a critical high-value intermediate for research and development. It is primarily sought by pharmaceutical researchers and advanced materials scientists exploring novel drug candidates, energetic materials, and polymers with tailored properties.

Application

• Pharmaceutical Intermediate: Serves as a sophisticated building block for the synthesis of novel bioactive molecules and drug candidates, leveraging the unique cubane scaffold for enhanced metabolic stability.
• Advanced Materials Research: Used in the development of high-density, high-strain polymers and specialty materials with unique optical or electronic properties.
• Energetic Materials Precursor: Acts as a key intermediate in the research and synthesis of novel high-energy-density materials (HEDMs) for specialized applications.
• Academic & Industrial R&D: A valuable tool for synthetic organic chemists in universities and corporate R&D labs studying strained hydrocarbon chemistry and novel reaction pathways.
• Ligand and Catalyst Development: The formyl and ester functional groups provide handles for further derivatization to create unique ligands for catalysis or molecular recognition.

Basic Information

Product Name	Methyl (1S,2R,3R,8S)-4-Formylcubane-1-Carboxylate
CAS No.	211635-35-7
Molecular Formula	C12H12O3
Molecular Weight	204.22 g/mol
Synonyms	Methyl 4-formylcubane-1-carboxylate; (1S,2R,3R,8S)-Methyl 4-formylcubane-1-carboxylate; Cubane-1,4-dicarboxylic acid, 1-methyl ester, 4-aldehyde; 4-Formylcubane-1-carboxylic acid methyl ester; Methyl (cubane-1,4-dicarboxylate) monoaldehyde; Cubane derivative, formyl-methyl ester
EINECS	Contact for details

Quality Control

Our production of this high-purity specialty chemical adheres to stringent quality assurance protocols. Each batch is characterized using advanced analytical techniques including NMR, HPLC, and GC-MS to confirm identity, isomeric purity, and chemical integrity. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profile is provided with every shipment to ensure traceability and meet the exacting standards of research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at controlled room temperature (15-25°C) in a cool, dry, and well-ventilated place. This compound is easily oxidized and light-sensitive; prolonged exposure to air or light should be avoided to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Isomeric Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.