Description

(R)-(+)-6,6'-Dibromo-2,2'-Bis(Methoxymethoxy)-1,1'-Binaphthyl CAS NO 211560-97-3 is a high-value, enantiomerically pure binaphthyl derivative, a crucial chiral building block in advanced organic synthesis. Its core value lies in its ability to impart axial chirality and serve as a sophisticated ligand precursor for asymmetric catalysis. This compound is essential for research and development chemists in the pharmaceutical and fine chemical industries, particularly those developing novel active pharmaceutical ingredients (APIs) and specialty materials where precise stereochemical control is paramount.

Application

• Asymmetric Catalysis: Serves as a key precursor for synthesizing chiral phosphine and N-heterocyclic carbene (NHC) ligands used in transition-metal-catalyzed reactions like cross-couplings and hydrogenations.
• Pharmaceutical Intermediate: A vital chiral scaffold in the multi-step synthesis of complex drug candidates, especially in oncology and central nervous system (CNS) therapeutic areas.
• Material Science Research: Used in the development of chiral organic frameworks, polymers, and liquid crystals with specific optical properties.
• Methodology Development: Employed by academic and industrial research groups to develop and optimize new enantioselective synthetic methodologies.
• Ligand Library Synthesis: A foundational structure for creating diverse libraries of chiral ligands for high-throughput screening in catalyst discovery.

Basic Information

Product Name	(R)-(+)-6,6'-Dibromo-2,2'-Bis(Methoxymethoxy)-1,1'-Binaphthyl
CAS No.	211560-97-3
Molecular Formula	C₂₄H₂₂Br₂O₄
Molecular Weight	534.24 g/mol
Synonyms	(R)-6,6'-Dibromo-2,2'-bis(methoxymethoxy)-1,1'-binaphthyl; (R)-(+)-6,6'-Dibromo-2,2'-di(methoxymethoxy)-1,1'-binaphthyl; (R)-BINOL-6,6'-dibromo-2,2'-dimethyl ether derivative; (R)-6,6'-Dibromo-BINOL MOM ether; 1,1'-Binaphthalene-2,2'-diol, 6,6'-dibromo-2,2'-bis(methoxymethoxy)-, (1R)-; (R)-6,6'-Dibromo-2,2'-bis(methoxymethoxy)-[1,1'-binaphthalene]; (R)-MOM-Protected 6,6'-DibromoBINOL
EINECS	Contact for details

Quality Control

Every batch of our (R)-(+)-6,6'-Dibromo-2,2'-Bis(Methoxymethoxy)-1,1'-Binaphthyl is produced and tested under strict quality management systems. We guarantee high enantiomeric excess (ee) and chemical purity to meet the rigorous demands of process chemistry and research. Comprehensive analytical data, including HPLC for purity/chirality, NMR, and MS, is provided with each Certificate of Analysis (COA), ensuring full traceability and compliance with your internal specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is light-sensitive; prolonged exposure to light should be avoided to maintain stability and enantiomeric purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH Q3C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.