Description

(R)-Chroman-3-Ylamine Hydrochloride is a high-purity chiral amine building block and pharmaceutical intermediate. This compound is valued for its role in the synthesis of enantiomerically pure molecules, particularly in medicinal chemistry and drug discovery. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries developing novel active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new therapeutic agents, including central nervous system (CNS) drugs and cardiovascular medications.
• Asymmetric Synthesis: Used as a chiral auxiliary or resolving agent in stereoselective chemical reactions to produce single-enantiomer compounds.
• Agrochemical Research: Serves as a building block for developing advanced, enantiopure pesticides and herbicides with improved efficacy and environmental profiles.
• Ligand and Catalyst Development: Employed in the design and synthesis of novel chiral ligands for catalytic processes like hydrogenation and cross-coupling reactions.
• Reference Standard: Used as an analytical standard in quality control (QC) and method development for chiral separation techniques (e.g., Chiral HPLC).
• Academic & R&D: A valuable reagent for universities and contract research organizations (CROs) exploring new synthetic methodologies and bioactive molecule libraries.

Basic Information

Product Name	(R)-Chroman-3-Ylamine Hydrochloride
CAS No.	211506-59-1
Molecular Formula	C9H12ClNO
Molecular Weight	185.65 g/mol
Synonyms	(R)-3-Aminochroman hydrochloride; (3R)-3-Amino-3,4-dihydro-2H-1-benzopyran hydrochloride; (R)-3-Amino-3,4-dihydro-2H-chromene hydrochloride; (R)-3-Chromanamine hydrochloride; (R)-3-Amino-3,4-dihydro-2H-1-benzopyran hydrochloride; (R)-2,3-Dihydro-3-amino-1-benzopyran hydrochloride; (R)-3-Amino-2,3-dihydrobenzopyran hydrochloride
EINECS	Contact for details

Quality Control

Our (R)-Chroman-3-Ylamine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for advanced synthetic applications. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and enantiomeric excess.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Chiral Purity (Enantiomeric Excess)	≥99.0% ee
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.