Description

3-Cyclobutylphenol is a versatile phenolic compound featuring a cyclobutyl substituent, offering a unique steric and electronic profile for advanced chemical synthesis. This intermediate is valued for its role in constructing complex molecular architectures, particularly in pharmaceutical research and fine chemical manufacturing. It serves as a critical building block for medicinal chemists and R&D professionals developing novel active pharmaceutical ingredients (APIs) and specialty organic compounds.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates and active pharmaceutical ingredients (APIs), especially those targeting central nervous system (CNS) disorders.
• Agrochemical Synthesis: Used in the research and development of new-generation pesticides and herbicides, leveraging the cyclobutyl moiety for enhanced biological activity.
• Ligand and Catalyst Development: Serves as a backbone for creating specialized ligands in asymmetric catalysis and organometallic chemistry.
• Material Science Research: Employed in the development of advanced polymers and functional materials where phenolic units are required.
• Fine Chemical Production: A valuable intermediate for manufacturing specialty chemicals, flavors, and fragrances.
• Academic & Industrial R&D: Essential for exploratory organic synthesis and method development in both university and corporate research laboratories.

Basic Information

Product Name	3-Cyclobutylphenol
CAS No.	211495-49-7
Molecular Formula	C10H12O
Molecular Weight	148.20 g/mol
Synonyms	3-Cyclobutylphenol; Phenol, 3-cyclobutyl-; m-Cyclobutylphenol; 1-Hydroxy-3-cyclobutylbenzene; 3-Cyclobutyl-1-hydroxybenzene; (3-Hydroxyphenyl)cyclobutane; Cyclobutylbenzene-3-ol
EINECS	Contact for details

Quality Control

Our 3-Cyclobutylphenol is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical documentation, including Certificates of Analysis (COA) with detailed results from GC, HPLC, and NMR analyses. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for critical research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.