Description

4-(Trifluoromethyl)Quinolin-2-Amine is a high-purity, specialized quinoline derivative featuring a reactive amine group and a trifluoromethyl substituent. This compound matters as a critical pharmaceutical intermediate and versatile building block for advanced organic synthesis, enabling the development of novel bioactive molecules. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and material science industries for creating new drug candidates, crop protection agents, and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting central nervous system (CNS) disorders, anti-infectives, and oncology.
• Agrochemical Research: Serves as a building block for developing novel herbicides, fungicides, and insecticides, leveraging the biological activity of the quinoline scaffold.
• Organic Light-Emitting Diodes (OLEDs): Used in the research and development of electron-transport or emissive layer materials for display and lighting technologies.
• Ligand Synthesis: Employed in the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Fluorescent Probe Development: Acts as a core structure for creating sensitive fluorescent dyes and probes used in biochemical assays and diagnostics.
• Academic & Contract Research: A valuable reagent for medicinal chemistry programs and structure-activity relationship (SAR) studies in academic and industrial R&D labs.

Basic Information

Product Name	4-(Trifluoromethyl)Quinolin-2-Amine
CAS No.	211449-19-3
Molecular Formula	C10H7F3N2
Molecular Weight	212.17 g/mol
Synonyms	2-Amino-4-(trifluoromethyl)quinoline; 4-(Trifluoromethyl)-2-quinolinamine; 2-Quinolinamine, 4-(trifluoromethyl)-; 4-Trifluoromethylquinolin-2-ylamine; 4-Trifluoromethyl-2-aminoquinoline; Quinolin-2-amine, 4-(trifluoromethyl)-; 211449-19-3
EINECS	Contact for details

Quality Control

Our 4-(Trifluoromethyl)Quinolin-2-Amine is produced under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure it meets the highest standards for purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment. We support compliance with cGMP and ISO guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.