Description

4(1H)-Quinazolinone, 8-Methoxy-2-[4-(Trifluoromethyl)Phenyl]- (9Ci) is a high-value, heterocyclic organic compound featuring a quinazolinone core substituted with methoxy and trifluoromethylphenyl groups. This specific molecular architecture makes it a critical pharmaceutical intermediate and a versatile scaffold for medicinal chemistry research. It is primarily sought after by R&D and production teams in the pharmaceutical and agrochemical industries for developing novel active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of potential drug candidates targeting various therapeutic areas.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Kinase Inhibitor Development: The quinazolinone structure is a privileged motif in the design of kinase inhibitors for oncology and inflammatory diseases.
• Agrochemical Research: Employed in the research and development of new herbicides, fungicides, or insecticides.
• Chemical Biology Probes: Utilized in the development of molecular probes to study biological pathways and protein function.
• Organic Synthesis: Acts as a specialized starting material or intermediate for synthesizing more complex heterocyclic compounds.

Basic Information

Product Name	4(1H)-Quinazolinone, 8-Methoxy-2-[4-(Trifluoromethyl)Phenyl]- (9Ci)
CAS No.	211172-83-7
Molecular Formula	C₁₆H₁₁F₃N₂O₂
Molecular Weight	320.27 g/mol
Synonyms	8-Methoxy-2-[4-(trifluoromethyl)phenyl]-4(1H)-quinazolinone; 2-[4-(Trifluoromethyl)phenyl]-8-methoxy-4(1H)-quinazolinone; 8-Methoxy-2-(4-trifluoromethylphenyl)-1,4-dihydroquinazolin-4-one; 211172-83-7; 8-Methoxy-2-(α,α,α-trifluoro-p-tolyl)-4(1H)-quinazolinone
EINECS	Contact for details

Quality Control

Our production of 4(1H)-Quinazolinone, 8-Methoxy-2-[4-(Trifluoromethyl)Phenyl]- (9Ci) adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR/IR for structural confirmation, to ensure consistency and compliance with research-grade specifications. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability and support your quality assurance processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.