Description

4(1H)-Quinazolinone, 8-Hydroxy-2-(4-Hydroxyphenyl)- (9Ci) is a specialized heterocyclic organic compound belonging to the quinazolinone class, which is a core scaffold of significant pharmaceutical interest. This compound matters as a key pharmacological intermediate and building block for the research and development of novel therapeutic agents. It is primarily needed by pharmaceutical R&D organizations, contract research organizations (CROs), and academic research institutions focused on medicinal chemistry and drug discovery.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of potential drug candidates targeting various diseases.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies to develop new enzyme inhibitors or receptor modulators.
• Kinase Inhibitor Development: A potential building block for compounds targeting tyrosine kinases and other kinase families relevant in oncology.
• Anti-inflammatory Agent Research: Investigated for its potential role in developing novel anti-inflammatory or immunomodulatory drugs.
• Anticancer Agent Synthesis: Explored in the synthesis of novel quinazolinone derivatives with potential cytotoxic activity.
• Biochemical Tool Compound: May be used in biochemical assays to study specific biological pathways and mechanisms.
• Reference Standard: Employed as an analytical standard in quality control and method development for related pharmaceutical products.

Basic Information

Product Name	4(1H)-Quinazolinone, 8-Hydroxy-2-(4-Hydroxyphenyl)- (9Ci)
CAS No.	211172-81-5
Molecular Formula	C15H10N2O3
Molecular Weight	266.25 g/mol
Synonyms	8-Hydroxy-2-(4-hydroxyphenyl)-4(1H)-quinazolinone; 2-(4-Hydroxyphenyl)-8-hydroxy-1,4-dihydroquinazolin-4-one; 8-Hydroxy-2-(4-hydroxyphenyl)quinazolin-4(1H)-one; 2-(4-Hydroxyphenyl)-8-hydroxy-4(1H)-quinazolinone; 4(1H)-Quinazolinone, 8-hydroxy-2-(4-hydroxyphenyl)-; 211172-81-5; 8-Hydroxy-2-(4'-hydroxyphenyl)-4(1H)-quinazolinone
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. We provide comprehensive analytical data to support research and development needs. Certificates of Analysis (COA) are available upon request, detailing purity, identity, and impurity profiles. Production can be aligned with cGMP guidelines for advanced pharmaceutical applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, long-term storage under an inert atmosphere (e.g., nitrogen or argon) is recommended for optimal stability.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.