Description

N4-(4-Boc-Aminobutyl)-3-Nitroqunoline-4-Amine is a specialized, high-purity chemical building block featuring a protected amine group and a nitroquinoline core. This compound is critical for advanced organic synthesis, particularly in the development of novel pharmaceutical agents and bioactive molecules. It is primarily utilized by research scientists and process chemists in the pharmaceutical, biotechnology, and fine chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the research and development of new drug candidates, particularly those targeting specific enzyme pathways.
• Protease Inhibitor Synthesis: Used in the construction of potential protease inhibitors due to the reactive nitroquinoline scaffold.
• Chemical Biology Probes: Acts as a precursor for developing labeled probes or affinity tags to study biological processes.
• Peptidomimetic Chemistry: The Boc-protected aminobutyl side chain makes it valuable for creating peptide-like structures with enhanced stability.
• Library Synthesis for HTS: Employed in generating diverse compound libraries for high-throughput screening in drug discovery programs.
• Agrochemical Research: Potential intermediate in the synthesis of novel active ingredients for crop protection.

Basic Information

Product Name	N4-(4-Boc-Aminobutyl)-3-Nitroqunoline-4-Amine
CAS No.	210303-93-8
Molecular Formula	C₁₈H₂₆N₄O₄
Molecular Weight	362.43 g/mol
Synonyms	N-(4-((tert-Butoxycarbonyl)amino)butyl)-3-nitroquinolin-4-amine; 4-[[4-[(2-Methyl-2-propanyloxycarbonyl)amino]butyl]amino]-3-nitroquinoline; tert-Butyl N-[4-[(3-nitroquinolin-4-yl)amino]butyl]carbamate; 3-Nitro-4-((4-(Boc-amino)butyl)amino)quinoline; Boc-4-AB-3-NQ; 210303-93-8; N4-(4-(Boc-amino)butyl)-3-nitro-4-quinolinamine
EINECS	Contact for details

Quality Control

Our N4-(4-Boc-Aminobutyl)-3-Nitroqunoline-4-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent degradation and moisture uptake.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.