Description

n-Acetyl-2,3-Dehydro-2-Deoxyneuraminic Acid Sodium Salt is a chemically modified derivative of neuraminic acid, serving as a key intermediate and reference standard in advanced biochemical research and synthesis. This compound is valued for its role in studying and inhibiting sialidase enzymes, which are crucial in various biological and pathological processes. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and diagnostic sectors for developing novel therapeutics and analytical methods.

Application

• Enzymology Research: Used as a substrate or inhibitor in studies of viral, bacterial, and mammalian sialidases (neuraminidases).
• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of more complex sialic acid analogs and potential drug candidates.
• Diagnostic Development: Employed in the design and calibration of assays for detecting enzymatic activity related to infectious diseases and metabolic disorders.
• Glycobiology Studies: Essential for investigating the role of sialic acids in cell signaling, immune response, and pathogen recognition.
• Antiviral Agent Research: Acts as a precursor or model compound for developing new neuraminidase inhibitors targeting influenza and other viruses.
• Bioconjugation & Probe Synthesis: Utilized to create labeled probes for imaging and studying sialic acid-binding proteins and receptors.

Basic Information

Product Name	n-Acetyl-2,3-Dehydro-2-Deoxyneuraminic Acid Sodium Salt
CAS No.	209977-53-7
Molecular Formula	C11H15NNaO8
Molecular Weight	312.23 g/mol
Synonyms	2-Deoxy-2,3-didehydro-N-acetylneuraminic Acid Sodium Salt; DANA Sodium Salt; Neu5Ac2en Sodium Salt; 5-Acetamido-2,6-anhydro-3,5-dideoxy-D-glycero-D-galacto-non-2-enonic Acid Sodium Salt; Zanamivir Intermediate; Sialic Acid Derivative Sodium Salt; Anti-Influenza Agent Intermediate
EINECS	Contact for details

Quality Control

Our n-Acetyl-2,3-Dehydro-2-Deoxyneuraminic Acid Sodium Salt is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and stringent controls for residual solvents and impurities. A Certificate of Analysis (COA) detailing all specifications is provided to ensure traceability and compliance with research-grade material standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider desiccated or inert atmosphere conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH limits

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.