Description

1-(3-Cyanophenyl)-3-(Trifluoromethyl)-1H-Pyrazole-5-Carboxylic Acid is a high-value, multi-functional heterocyclic building block essential for advanced organic synthesis. Its molecular structure, featuring a cyano group, a trifluoromethyl-substituted pyrazole ring, and a carboxylic acid moiety, makes it a versatile intermediate for creating compounds with tailored properties. This product is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients, where its unique scaffold can impart critical bioactivity and metabolic stability.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly for targets requiring trifluoromethyl and nitrile functional groups to enhance binding affinity and pharmacokinetic properties.
• Agrochemical Research: Used in developing new generations of herbicides, fungicides, and insecticides, where the pyrazole core is a common pharmacophore for biological activity.
• Material Science: Serves as a building block for advanced organic materials, such as ligands for catalysts or monomers for specialty polymers with specific electronic or thermal characteristics.
• Chemical Synthesis: Employed in academic and industrial R&D for constructing complex heterocyclic systems, leveraging its carboxylic acid group for further derivatization via amidation or esterification.
• Ligand & Chelator Development: The pyrazole nitrogen atoms and carboxylic acid group make it a candidate for designing novel chelating agents or metal-organic frameworks (MOFs).

Basic Information

Product Name	1-(3-Cyanophenyl)-3-(Trifluoromethyl)-1H-Pyrazole-5-Carboxylic Acid
CAS No.	209917-93-1
Molecular Formula	C12H6F3N3O2
Molecular Weight	281.19 g/mol
Synonyms	3-(Trifluoromethyl)-1-(3-cyanophenyl)-1H-pyrazole-5-carboxylic acid; 1H-Pyrazole-5-carboxylic acid, 1-(3-cyanophenyl)-3-(trifluoromethyl)-; 1-(3-Cyanophenyl)-3-(trifluoromethyl)pyrazole-5-carboxylic acid; 5-Carboxy-1-(3-cyanophenyl)-3-(trifluoromethyl)pyrazole; 209917-93-1; 3-CF3-1-(3-CN-Ph)-Pyrazole-5-COOH
EINECS	Contact for details

Quality Control

Our production of 1-(3-Cyanophenyl)-3-(Trifluoromethyl)-1H-Pyrazole-5-Carboxylic Acid adheres to stringent internal quality standards to ensure batch-to-batch consistency and high purity, critical for sensitive R&D and scale-up processes. All batches are analyzed using advanced techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent decomposition. Keep away from strong acids and organic solvents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.