Description

(S)-3-Amino-1,2-Dihydroxypropane Hydrochloride is a high-purity chiral building block and intermediate of significant importance in asymmetric synthesis. This compound is valued for its role in constructing complex molecules with defined stereochemistry, which is critical for biological activity. It is primarily needed by pharmaceutical, agrochemical, and fine chemical research and development sectors for the production of active pharmaceutical ingredients (APIs), ligands, and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of β-blockers, antiviral agents, and other bioactive molecules requiring precise stereocontrol.
• Ligand Synthesis: Used in the preparation of chiral ligands for asymmetric catalysis, enhancing the efficiency and selectivity of chemical transformations.
• Fine Chemical Production: Serves as a building block for specialty chemicals, flavors, and fragrances where enantiomeric purity is essential.
• Agrochemical Research: Employed in developing chiral active ingredients for herbicides and pesticides with improved efficacy and environmental profiles.
• Bioconjugation and Linker Chemistry: Utilized for modifying biomolecules due to its reactive amino and hydroxyl functional groups.
• Academic and R&D Laboratories: A valuable reagent for methodological development in organic synthesis and medicinal chemistry.

Basic Information

Product Name	(S)-3-Amino-1,2-Dihydroxypropane Hydrochloride
CAS No.	209849-99-0
Molecular Formula	C₃H₁₀ClNO₂
Molecular Weight	127.57 g/mol
Synonyms	(S)-3-Amino-1,2-propanediol hydrochloride; (S)-Aminopropanediol hydrochloride; (S)-1,2-Dihydroxy-3-aminopropane hydrochloride; (S)-3-Amino-1,2-dihydroxypropane HCl; (S)-3-Aminopropane-1,2-diol hydrochloride; L-Aminopropanediol hydrochloride; (2S)-3-Amino-1,2-propanediol hydrochloride
EINECS	Contact for details

Quality Control

Our (S)-3-Amino-1,2-Dihydroxypropane Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification, to ensure it meets the high standards required for research and production. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided to guarantee consistent quality and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.