Description

5-Chloro-1-(Phenylsulfonyl)-4-Azaindole is a high-purity, advanced pharmaceutical intermediate belonging to the azaindole class of heterocyclic compounds. Its unique sulfonylated structure makes it a critical building block for medicinal chemistry research and the synthesis of novel active pharmaceutical ingredients (APIs). This compound is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and biotechnology industries for developing new therapeutic agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly kinase inhibitors and other targeted therapies.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Chemical Biology Probe Development: Used to create tool compounds for studying biological pathways and target validation.
• Organic Synthesis Building Block: Employed in multi-step synthetic routes to construct more complex nitrogen-containing heterocycles.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and scale-up of pharmaceutical intermediates.

Basic Information

Product Name	5-Chloro-1-(Phenylsulfonyl)-4-Azaindole
CAS No.	209286-85-1
Molecular Formula	C13H9ClN2O2S
Molecular Weight	292.74 g/mol
Synonyms	1-(Phenylsulfonyl)-5-chloro-1H-pyrrolo[3,2-c]pyridine; 5-Chloro-1H-pyrrolo[3,2-c]pyridine 1-(phenylsulfonyl)-; 5-Chloro-1-(benzenesulfonyl)-1H-pyrrolo[3,2-c]pyridine; 5-Chloro-1-(phenylsulfonyl)-1H-pyrrolo[3,2-c]pyridine; 5-Chloro-1-(phenylsulfonyl)-4-aza-indole; 5-Chloro-1-(phenylsulfonyl)-4-azaindole; 5-Chloro-1-(phenylsulfonyl)pyrrolo[3,2-c]pyridine
EINECS	Contact for details

Quality Control

Our 5-Chloro-1-(Phenylsulfonyl)-4-Azaindole is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring GMP-grade intermediates and research-grade materials.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.