Description

7-(Bromomethyl)-1-Chloroisoquinoline is a versatile and high-value halogenated isoquinoline derivative, serving as a critical building block in advanced organic synthesis. Its bifunctional reactivity, featuring both a reactive bromomethyl group and a chloro-substituted heterocycle, makes it indispensable for constructing complex molecular architectures. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders, oncology, and infectious diseases.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the isoquinoline scaffold's bioactivity.
• Ligand and Catalyst Synthesis: Employed to create sophisticated ligands for metal catalysis and organocatalysts for asymmetric synthesis.
• Material Science: Serves as a monomer or functionalizing agent in the production of specialty polymers, OLED materials, and liquid crystals.
• Chemical Biology Probes: Utilized to develop molecular probes and tags for studying biological processes and protein function.
• Cross-Coupling Reactions: Acts as a versatile electrophile in Suzuki, Stille, and Buchwald-Hartwig amination reactions to form carbon-carbon and carbon-heteroatom bonds.

Basic Information

Product Name	7-(Bromomethyl)-1-Chloroisoquinoline
CAS No.	209285-92-7
Molecular Formula	C10H7BrClN
Molecular Weight	256.52 g/mol
Synonyms	1-Chloro-7-(bromomethyl)isoquinoline; 7-Bromomethyl-1-chloroisoquinoline; 1-Chloro-7-bromomethylisoquinoline; Isoquinoline, 1-chloro-7-(bromomethyl)-; 209285-92-7; 1-Chloro-7-(bromomethyl)isoquinoline
EINECS	Contact for details

Quality Control

We maintain stringent quality control protocols for our fine chemical intermediates. Every batch of 7-(Bromomethyl)-1-Chloroisoquinoline is analyzed using advanced techniques like HPLC, GC, and NMR to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment. Our quality system is designed to support cGMP-compliant applications for pharmaceutical R&D.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber-colored or stored in light-resistant packaging.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/IR)	Conforms to standard
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.