Description

4-Bromo-2,3-Dihydro-1H-Indene-2-Carboxylic Acid is a versatile and high-value brominated indane derivative, serving as a critical chiral building block in advanced organic synthesis. Its unique fused bicyclic structure with a carboxylic acid functional group makes it indispensable for constructing complex molecular architectures with precise stereochemistry. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and sophisticated materials chemistry.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel therapeutic agents, particularly in central nervous system (CNS) and cardiovascular drug candidates.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and pesticides, leveraging its bromine atom for further functionalization.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the development of organic semiconductors, liquid crystals, and other functional organic materials.
• Chemical Biology Probes: Utilized as a scaffold for creating molecular probes to study enzyme function and biological pathways.
• Custom Synthesis and Scale-Up: A foundational material for contract research and manufacturing organizations (CROs/CMOs) performing custom synthesis for clients.

Basic Information

Product Name	4-Bromo-2,3-Dihydro-1H-Indene-2-Carboxylic Acid
CAS No.	209224-95-3
Molecular Formula	C10H9BrO2
Molecular Weight	241.08 g/mol
Synonyms	4-Bromoindane-2-carboxylic Acid; 2,3-Dihydro-1H-indene-2-carboxylic Acid, 4-bromo-; 4-Bromo-2,3-dihydro-1H-indene-2-carboxylic acid; 4-Bromo-2-indancarboxylic Acid; 4-Bromo-2,3-dihydro-H-indene-2-carboxylic acid; 4-Bromoindan-2-carboxylic Acid; (4-Bromo-2,3-dihydro-1H-inden-2-yl)formic acid
EINECS	Contact for details

Quality Control

Our 4-Bromo-2,3-Dihydro-1H-Indene-2-Carboxylic Acid is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with each shipment, ensuring traceability and compliance with your research or production specifications. Our quality commitment supports applications requiring high-purity intermediates under cGMP or ISO 9001 guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.