Description

8-Azabicyclo[3.2.1]Octane-8-Carboxylicacid,3-Amino-,Ethylester,(3-Exo)- is a high-purity, advanced pharmaceutical intermediate with a complex bicyclic structure. This compound is valued for its role as a critical building block in the synthesis of active pharmaceutical ingredients (APIs), particularly those targeting the central nervous system. It is essential for research and development chemists and manufacturers in the pharmaceutical and fine chemical industries seeking reliable, high-quality intermediates for complex synthetic routes.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of novel therapeutic agents, including tropane alkaloid derivatives.
• Neurological Drug Research: Used in the R&D of potential treatments for neurological disorders, leveraging its bridged bicyclic amine scaffold.
• Asymmetric Synthesis: Serves as a precursor for chiral ligands or catalysts in stereoselective synthesis due to its defined stereochemistry.
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies and lead optimization for new drug candidates.
• Fine Chemical Production: Used in the multi-step synthesis of complex, high-value specialty chemicals.
• Contract Research & Manufacturing (CRAM): Supplied to organizations offering custom synthesis and process development services.

Basic Information

Product Name	8-Azabicyclo[3.2.1]Octane-8-Carboxylicacid,3-Amino-,Ethylester,(3-Exo)-
CAS No.	208046-26-8
Molecular Formula	C10H18N2O2
Molecular Weight	198.26 g/mol
Synonyms	(3-Exo)-3-Amino-8-azabicyclo[3.2.1]octane-8-carboxylic Acid Ethyl Ester; Ethyl (3-exo)-3-amino-8-azabicyclo[3.2.1]octane-8-carboxylate; 8-Azabicyclo[3.2.1]octane-8-carboxylic acid, 3-amino-, ethyl ester, (3-exo)-; 3-Amino-8-azabicyclo[3.2.1]octane-8-carboxylic acid ethyl ester (exo); 8-N-Boc-3-exo-amino-8-azabicyclo[3.2.1]octane (related protected form); Tropane-3-amine derivative; exo-3-Amino-8-azabicyclo[3.2.1]octane-8-carboxylate ethyl ester
EINECS	Contact for details

Quality Control

Our 8-Azabicyclo[3.2.1]Octane-8-Carboxylicacid,3-Amino-,Ethylester,(3-Exo)- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity and impurity profile analysis, to ensure it meets the high standards required for pharmaceutical R&D and production. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and related substances is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if specified. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (Chiral HPLC)	≥99.0% ee (exo-isomer)
Related Substances (HPLC)	Total impurities ≤2.0% Any single unknown impurity ≤0.5%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.