Description

5-(2,2-Dimethyl-1,3-Dioxolan-4-Yl)-2,2-Dimethyltetrahydrofuro[2,3-D][1,3]Dioxol-6-Ol is a sophisticated chiral building block and protected sugar derivative of significant interest in advanced organic synthesis. Its complex, multi-cyclic acetal-protected structure makes it a high-value intermediate for the production of complex natural products, nucleoside analogs, and novel pharmaceuticals. This compound is primarily utilized by research institutions and industrial R&D departments focused on asymmetric synthesis, carbohydrate chemistry, and medicinal chemistry.

Application

• Pharmaceutical Intermediate: Serves as a key chiral precursor in the synthesis of nucleoside-based antiviral or anticancer agents.
• Asymmetric Synthesis: Used as a versatile chiral auxiliary or building block for constructing complex molecules with defined stereochemistry.
• Carbohydrate Chemistry Research: Acts as a protected sugar derivative for studying glycosylation reactions and synthesizing complex oligosaccharides.
• Natural Product Synthesis: Employed in the total synthesis of natural products containing intricate furanose or dioxolane motifs.
• Chemical Biology Probes: Utilized in the development of labeled or modified sugars for probing biological pathways and enzyme mechanisms.
• Process Chemistry Development: Investigated for scalable routes to high-value fine chemicals and active pharmaceutical ingredients (APIs).

Basic Information

Product Name	5-(2,2-Dimethyl-1,3-Dioxolan-4-Yl)-2,2-Dimethyltetrahydrofuro[2,3-D][1,3]Dioxol-6-Ol
CAS No.	207855-12-7
Molecular Formula	C13H22O6
Molecular Weight	274.31 g/mol
Synonyms	1,2:5,6-Di-O-isopropylidene-α-D-glucofuranose (common name); 1,2:5,6-Di-O-isopropylidene-α-D-glucofuranose; Diacetone-D-glucose; Diacetone glucose; α-D-Glucofuranose, 1,2:5,6-di-O-(1-methylethylidene)-; 1,2:5,6-Di-O-isopropylidene-α-D-allofuranose (related isomer); D-Glucose diacetonide
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems. Each batch is characterized and tested using advanced analytical techniques including HPLC, GC, NMR, and optical rotation measurement to ensure high chemical and chiral purity. Certificates of Analysis (COA) detailing identity, purity, and specific parameters are provided with every shipment. We support development and cGMP-grade production for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere if necessary for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Optical Rotation [α]²⁰D	-18° to -22° (c=1 in H₂O)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.