Description

2,3,4-Trifluorocinnamic Acid is a high-purity fluorinated aromatic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key precursor in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where the trifluoromethylphenyl moiety can dramatically influence biological activity and metabolic stability. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty materials industries for constructing complex molecules with tailored properties.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of fluorinated drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides and pesticides, where fluorine atoms enhance efficacy and environmental persistence.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated components in electronic display materials, improving thermal stability and optical performance.
• Polymer Modification: Incorporated into specialty polymers to impart unique chemical resistance, lower dielectric constants, or altered surface properties.
• Chemical Research & Development: Employed in academic and industrial R&D labs for exploring new fluorination methodologies and structure-activity relationships (SAR).
• Peptide Mimetics & Bio-conjugates: Utilized to introduce fluorinated cinnamic acid derivatives into peptides or other biomolecules to study protein interactions or create probes.

Basic Information

Product Name	2,3,4-Trifluorocinnamic Acid
CAS No.	207742-85-6
Molecular Formula	C9H5F3O2
Molecular Weight	202.13 g/mol
Synonyms	(2E)-3-(2,3,4-Trifluorophenyl)prop-2-enoic acid; trans-2,3,4-Trifluorocinnamic Acid; 2,3,4-Trifluorocinnameic Acid; β-(2,3,4-Trifluorophenyl)acrylic Acid; 3-(2,3,4-Trifluorophenyl)-2-propenoic Acid; (E)-3-(2,3,4-Trifluorophenyl)acrylic Acid; 2,3,4-Trifluoro-trans-cinnamic Acid
EINECS	Contact for details

Quality Control

Our 2,3,4-Trifluorocinnamic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and consistent lot-to-lot performance. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your quality and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible materials. The container must be kept tightly closed to prevent contamination and moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.