Description

L-Serine, n-Methyl-, Methyl Ester, Hydrochloride (1:1) is a high-purity, protected amino acid derivative essential for advanced organic synthesis and peptide research. This compound serves as a critical building block for constructing complex peptides and modified biomolecules with precise stereochemistry. It is primarily utilized by pharmaceutical R&D teams, biotechnology companies, and fine chemical manufacturers developing novel therapeutic agents and biochemical tools.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of novel peptide-based drugs and active pharmaceutical ingredients (APIs).
• Peptide Synthesis: Used in Solid-Phase Peptide Synthesis (SPPS) and solution-phase methods to introduce modified serine residues into peptide chains.
• Biochemical Research: Employed in proteomics and enzymology studies to investigate post-translational modifications like methylation.
• Prodrug Development: Acts as a precursor or protecting group strategy in the design of prodrugs to enhance bioavailability and stability.
• Agrochemical Synthesis: Serves as an intermediate in the production of specialized, bioactive compounds for crop protection.
• Reference Standard: Used as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	L-Serine, n-Methyl-, Methyl Ester, Hydrochloride (1:1)
CAS No.	207570-19-2
Molecular Formula	C5H12ClNO3
Molecular Weight	169.61 g/mol
Synonyms	Methyl (2S)-2-(methylamino)-3-hydroxypropanoate hydrochloride; L-N-Methylserine methyl ester hydrochloride; (S)-Methyl 2-(methylamino)-3-hydroxypropanoate hydrochloride; Methyl O-serinate, N-methyl-, hydrochloride; H-Ser(Me)-OMe·HCl; N-Methyl-L-serine methyl ester hydrochloride; N-Me-L-Ser-OMe·HCl
EINECS	Contact for details

Quality Control

Our L-Serine, n-Methyl-, Methyl Ester, Hydrochloride (1:1) is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the stringent requirements for pharmaceutical and research applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere in a desiccator.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% (L-isomer)
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.