Description

2-Propenenitrile,3-[(1S)-2,6,6-Trimethyl-2-Cyclohexen-1-Yl]-(9Ci) is a specialized chiral nitrile derivative of a trimethylcyclohexene structure, serving as a high-value synthetic intermediate. This compound is critical for enabling precise stereochemistry in advanced organic synthesis, where its defined configuration ensures the production of enantiomerically pure target molecules. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for the synthesis of complex bioactive molecules and fragrances.

Application

• Pharmaceutical Intermediate: Key chiral building block for the synthesis of novel active pharmaceutical ingredients (APIs) and drug candidates.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides with specific stereochemical requirements.
• Fine Chemical Production: Serves as a precursor in the manufacture of complex fragrance and flavor compounds.
• Academic & Industrial Research: A valuable reagent for methodological studies in asymmetric synthesis and catalysis.
• Material Science: Potential monomer or modifier in the development of specialized polymers with unique optical or chemical properties.

Basic Information

Product Name	2-Propenenitrile,3-[(1S)-2,6,6-Trimethyl-2-Cyclohexen-1-Yl]-(9Ci)
CAS No.	207226-91-3
Molecular Formula	C12H17N
Molecular Weight	175.27 g/mol
Synonyms	(S)-3-(2,6,6-Trimethylcyclohex-2-en-1-yl)acrylonitrile; (1S)-3-(2,6,6-Trimethyl-2-cyclohexen-1-yl)-2-propenenitrile; (S)-β-Iononitrile; (S)-3-(2,6,6-Trimethyl-1-cyclohexen-1-yl)acrylonitrile; (S)-Cyclohexeneacrylonitrile derivative; Chiral Ionone nitrile; (S)-Form of a C13-nitrile; Contact for details on additional trade names.
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. We provide material with a typical purity of ≥97% (by HPLC), with chiral purity (enantiomeric excess, e.e.) being a critical control parameter. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request. Production can adhere to cGMP guidelines for advanced pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Recommended storage temperature is 2-8°C for long-term stability. The compound is moisture-sensitive (hygroscopic) and should be handled under an inert atmosphere for optimal shelf-life.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (e.e.)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.