Description

tert-Butyl 4-(5,6,7,8-Tetrahydro-1,8-Naphthyridin-2-Yl)Piperidine-1-Carboxylate CAS NO 206989-63-1 is a high-purity, advanced pharmaceutical intermediate featuring a complex bicyclic naphthyridine-piperidine scaffold. This compound is of significant value for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated molecular architectures. It is primarily sought by research institutions and pharmaceutical companies engaged in the development of new drug candidates, especially within oncology and central nervous system (CNS) research.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the multi-step synthesis of complex drug molecules and investigational new drugs (INDs).
• Medicinal Chemistry Research: Used extensively in lead optimization and structure-activity relationship (SAR) studies to develop new therapeutic agents.
• API Synthesis: A key building block for constructing the core scaffold of target APIs, particularly those with kinase inhibitor or receptor modulator activity.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and process development services for the pharmaceutical industry.
• Academic Research: Utilized in university and institutional labs for studying heterocyclic chemistry and developing new synthetic methodologies.
• Pre-clinical Development: Employed in the synthesis of compounds for pharmacological profiling and toxicology studies.

Basic Information

Product Name	tert-Butyl 4-(5,6,7,8-Tetrahydro-1,8-Naphthyridin-2-Yl)Piperidine-1-Carboxylate
CAS No.	206989-63-1
Molecular Formula	C19H27N3O2
Molecular Weight	329.44 g/mol
Synonyms	1-Boc-4-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)piperidine; tert-Butyl 4-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)piperidine-1-carboxylate; 1,8-Naphthyridine-2-piperidinecarboxylic acid, 5,6,7,8-tetrahydro-, 1,1-dimethylethyl ester; 4-(5,6,7,8-Tetrahydro-1,8-naphthyridin-2-yl)piperidine-1-carboxylic acid tert-butyl ester; 2-(1-Boc-4-piperidyl)-5,6,7,8-tetrahydro-1,8-naphthyridine; BOC-protected 4-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)piperidine
EINECS	Contact for details

Quality Control

Every batch of tert-Butyl 4-(5,6,7,8-Tetrahydro-1,8-Naphthyridin-2-Yl)Piperidine-1-Carboxylate is manufactured and tested under a strict quality management system. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency that meet the exacting standards required for pharmaceutical research and development. A comprehensive Certificate of Analysis (COA) detailing all specifications and test results is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.