Description

4-Chloro-3-Fluorophenethyl Alcohol is a versatile fluorinated aromatic building block of significant importance in advanced organic synthesis. Its molecular structure, featuring both chloro and fluoro substituents on the phenethyl alcohol backbone, makes it a critical intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting CNS disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides, where the fluorine atom enhances biological activity and environmental stability.
• Liquid Crystal Materials: Serves as a precursor for fluorinated mesogens used in display technologies, improving dielectric anisotropy and thermal stability.
• Organic Electronics: Employed in the development of charge-transport materials and semiconductors for OLEDs and OFETs.
• Chemical Research: A valuable reagent for method development in cross-coupling reactions and other catalytic transformations involving halogenated aromatics.
• Fine Chemical Production: Acts as a building block for specialty polymers, dyes, and complex fragrance molecules.

Basic Information

Item	Detail
Product Name	4-Chloro-3-Fluorophenethyl Alcohol
CAS No.	206362-79-0
Molecular Formula	C8H8ClFO
Molecular Weight	174.60 g/mol
Synonyms	2-(4-Chloro-3-fluorophenyl)ethan-1-ol; 4-Chloro-3-fluorobenzeneethanol; 2-(4-Chloro-3-fluorophenyl)ethanol; (4-Chloro-3-fluorophenyl)ethyl alcohol; 4-Chloro-3-fluoro-phenethyl alcohol; 4-Chloro-3-fluoro-β-phenethyl alcohol; 4-Chloro-3-fluoro-2-phenylethanol
EINECS	Contact for details

Quality Control

Our 4-Chloro-3-Fluorophenethyl Alcohol is manufactured under a strict quality management system to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and impurity profiling, GC for residual solvents, and spectroscopic identification. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee compliance with your specifications and industry standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after each use to prevent moisture absorption, which may affect product stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.