Description

o-(2-Aminoethyl)-O'-(2-(Boc-Amino)Ethyl) is a specialized bifunctional amine derivative, primarily used as a versatile building block in advanced organic synthesis. Its core value lies in providing a protected amine handle and a free primary amine on a flexible ethylene glycol-like spacer, enabling controlled conjugation and polymer modification. This compound is essential for researchers and manufacturers in the pharmaceutical and bioconjugation sectors, particularly for developing peptide mimetics, creating functionalized polymers, and synthesizing complex drug-linker systems.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel active pharmaceutical ingredients (APIs), especially in oncology and targeted therapies.
• Bioconjugation & Linker Chemistry: Used to create cleavable or non-cleavable linkers for antibody-drug conjugates (ADCs), peptide-drug conjugates, and protein labeling.
• Polymer Functionalization: Serves as a monomer or modifier to introduce amine functionality into polyethylene glycol (PEG) derivatives, dendrimers, and other polymeric materials.
• Peptidomimetic Synthesis: Employed in constructing scaffolds that mimic peptide structures for drug discovery and biochemical probes.
• Surface Modification: Facilitates the amine-functionalization of surfaces, nanoparticles, and resins for biosensor development and chromatography media.
• Cross-linking Agent: Acts as a heterobifunctional cross-linker for coupling biomolecules or materials with different functional groups.

Basic Information

Product Name	o-(2-Aminoethyl)-O'-(2-(Boc-Amino)Ethyl)
CAS No.	206265-98-7
Molecular Formula	C11H24N2O3
Molecular Weight	232.32 g/mol
Synonyms	1,2-Ethanediamine, N1-[2-[[(1,1-dimethylethoxy)carbonyl]amino]ethyl]-N2-(2-aminoethyl)-; 2,2'-(Ethylenedioxy)bis(ethylamine), N-Boc protected; N-Boc-3-oxa-1,5-pentanediamine; Boc-NH-PEG2-amine; 2-[2-(Boc-amino)ethoxy]ethylamine; Amino-PEG2-Boc; 3-Oxa-1,5-pentanediamine, N1-Boc; Heterobifunctional PEG amine, Boc-protected
EINECS	Contact for details

Quality Control

Our o-(2-Aminoethyl)-O'-(2-(Boc-Amino)Ethyl) is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for research and cGMP manufacturing. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as specified on the label. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. Keep container tightly sealed in a desiccated environment when not in use.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Assay (Titration)	≥ 97.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.