Description

8-Bromo-4-Chloroquinoline-3-Carboxylic Acid Ethyl Ester is a high-purity, multi-functional heterocyclic building block essential for advanced organic synthesis. This compound is valued for its reactive halogen sites and ester functionality, enabling precise molecular construction in complex chemical environments. It is primarily sought by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex quinoline-based drug candidates, including potential antimicrobial and anticancer agents.
• Agrochemical Research: Used in the development of new herbicides and pesticides, leveraging its halogenated quinoline core for bioactivity.
• Material Science: Serves as a building block for creating functionalized organic molecules used in advanced materials, such as organic semiconductors or ligands for catalysis.
• Chemical Synthesis: Utilized in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic substitution reactions due to its reactive bromo and chloro substituents.
• Academic & R&D: Employed in university and corporate research laboratories for methodological studies and the exploration of new heterocyclic chemistry.

Basic Information

Product Name	8-Bromo-4-Chloroquinoline-3-Carboxylic Acid Ethyl Ester
CAS No.	206258-97-1
Molecular Formula	C₁₂H₉BrClNO₂
Molecular Weight	314.56 g/mol
Synonyms	Ethyl 8-Bromo-4-chloroquinoline-3-carboxylate; 8-Bromo-4-chloro-3-quinolinecarboxylic acid ethyl ester; 3-Quinolinecarboxylic acid, 8-bromo-4-chloro-, ethyl ester; 206258-97-1; Ethyl 8-bromo-4-chloroquinoline-3-carboxylate
EINECS	Contact for details

Quality Control

Our 8-Bromo-4-Chloroquinoline-3-Carboxylic Acid Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR/IR for structural confirmation, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). The compound may be light-sensitive; prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.