Description

4-Chloro-6-Iodo-Quinoline-3-Carboxylic Acid Ethyl Ester is a high-purity, multi-functional quinoline derivative serving as a critical building block in advanced organic synthesis. Its unique halogenated structure makes it an invaluable intermediate for the development of novel pharmaceutical compounds and functional materials. This product is essential for research and development chemists, process chemists, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to create complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds targeting infectious diseases, cancer, and central nervous system disorders.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the bioactivity of the quinoline scaffold.
• Material Science: Serves as a building block for creating organic light-emitting diodes (OLEDs), liquid crystals, and other advanced functional materials.
• Chemical Synthesis: Utilized in cross-coupling reactions (e.g., Suzuki, Sonogashira) and as a versatile substrate for further functionalization due to its reactive chlorine and iodine substituents.
• Academic & Contract Research: A valuable reagent for medicinal chemistry programs and method development in university and CRO (Contract Research Organization) laboratories.

Basic Information

Product Name	4-Chloro-6-Iodo-Quinoline-3-Carboxylic Acid Ethyl Ester
CAS No.	206257-60-5
Molecular Formula	C₁₂H₉ClINO₂
Molecular Weight	361.56 g/mol
Synonyms	Ethyl 4-Chloro-6-iodoquinoline-3-carboxylate; 4-Chloro-6-iodoquinoline-3-carboxylic acid ethyl ester; 3-Quinolinecarboxylic acid, 4-chloro-6-iodo-, ethyl ester; 206257-60-5; Ethyl 4-chloro-6-iodo-3-quinolinecarboxylate; 4-Chloro-6-iodo-3-quinolinecarboxylic acid ethyl ester; 4-Chloro-6-iodoquinoline-3-carboxylate ethyl ester
EINECS	Contact for details

Quality Control

Our 4-Chloro-6-Iodo-Quinoline-3-Carboxylic Acid Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis to ensure it meets the high standards required for research and production. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.