Description

Ethyl 6-Bromo-4-Chloro-3-Quinolinecarboxylate is a high-purity, multi-halogenated quinoline derivative serving as a critical advanced intermediate in modern organic synthesis. Its molecular architecture, featuring strategically positioned bromo and chloro substituents, makes it an invaluable building block for constructing complex heterocyclic systems. This compound is primarily sought after by research institutions and pharmaceutical R&D departments for the development of novel active pharmaceutical ingredients (APIs) and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of quinoline-based drug candidates, particularly for anticancer, antimicrobial, and anti-inflammatory applications.
• Agrochemical Research: Used in developing new generations of herbicides, fungicides, and pesticides with enhanced efficacy.
• Material Science: Serves as a monomer or functional unit in the creation of organic semiconductors, luminescent materials, and metal-organic frameworks (MOFs).
• Chemical Synthesis: Acts as a versatile electrophile in cross-coupling reactions (e.g., Suzuki, Stille) and nucleophilic substitution reactions to introduce the quinoline scaffold.
• Academic & Contract Research: Essential for methodological studies in heterocyclic chemistry and for creating specialized compound libraries for high-throughput screening.

Basic Information

Product Name	Ethyl 6-Bromo-4-Chloro-3-Quinolinecarboxylate
CAS No.	206257-39-8
Molecular Formula	C₁₂H₉BrClNO₂
Molecular Weight	314.56 g/mol
Synonyms	6-Bromo-4-chloroquinoline-3-carboxylic acid ethyl ester; Ethyl 6-bromo-4-chloro-3-quinolinecarboxylate; 3-Quinolinecarboxylic acid, 6-bromo-4-chloro-, ethyl ester; 6-Bromo-4-chloro-quinoline-3-carboxylic acid ethyl ester; Ethyl 6-bromo-4-chloroquinoline-3-carboxylate; 206257-39-8; 4-Chloro-6-bromoquinoline-3-carboxylic acid ethyl ester
EINECS	Contact for details

Quality Control

Our Ethyl 6-Bromo-4-Chloro-3-Quinolinecarboxylate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be light-sensitive; prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.