Description

Benzoylecgonine-D8 is a high-purity, stable isotope-labeled internal standard critical for modern analytical chemistry. This deuterated compound is essential for ensuring the accuracy, precision, and reliability of quantitative analyses in complex matrices. It is primarily used by analytical laboratories, forensic toxicologists, and pharmaceutical researchers who require definitive identification and measurement of its non-deuterated counterpart. The product is supplied to meet the stringent demands of regulated environments.

Application

• Quantitative Mass Spectrometry: Serves as an essential internal standard for the precise quantification of benzoylecgonine (a primary cocaine metabolite) in LC-MS/MS and GC-MS methods.
• Forensic Toxicology: Enables accurate and legally defensible analysis of urine, blood, and hair samples in workplace drug testing, post-mortem investigations, and criminal justice cases.
• Clinical Research: Used in pharmacokinetic and pharmacodynamic studies to monitor drug metabolism and exposure levels with high specificity.
• Method Development & Validation: Critical for developing, optimizing, and validating new analytical procedures, ensuring method robustness and regulatory compliance.
• Environmental & Wastewater Analysis: Applied in epidemiology studies to measure community drug usage patterns through the analysis of sewage and wastewater.
• Pharmaceutical Impurity Profiling: Aids in the identification and quantification of potential genotoxic impurities or metabolites in drug substances and products.
• Quality Control & Assurance: Supports in-house QC laboratories in maintaining the accuracy of their testing protocols and instrumentation calibration.

Basic Information

Product Name	Benzoylecgonine-D8
CAS No.	205446-21-5
Molecular Formula	C16H11D8NO4
Molecular Weight	297.37 g/mol
Synonyms	(-)-Benzoylecgonine-D8; 3β-Hydroxy-1αH,5αH-tropane-2β-carboxylic Acid Benzoate-D8; Benzoylecgonine (Phenyl-D5, Methyl-D3); Cocaine Metabolite-D8; Ecgonine Benzoate-D8; BZE-D8; d8-Benzoylecgonine
EINECS	Contact for details

Quality Control

Every batch of Benzoylecgonine-D8 is manufactured and analyzed under strict quality management systems. We provide comprehensive Certificates of Analysis (COA) that detail critical parameters including isotopic purity, chemical purity, and identity confirmation. Our quality protocols are designed to support compliance with ISO 17025 and FDA guidelines for analytical reference materials, ensuring data integrity for our clients' most demanding applications.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below. Allow the product to equilibrate to room temperature in a dry environment before opening to minimize moisture uptake. Keep the container in a secure, well-ventilated area designated for laboratory chemicals.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to reference spectrum
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D-content)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.