Description

(3S,5R,7Ar)-5-(Benzotriazol-1-Yl)-3-Phenyl[2,1-B]Oxazolopyrrolidine CAS NO 205442-89-3 is a high-purity, advanced pharmaceutical intermediate characterized by a complex fused heterocyclic structure. This compound is of significant value in medicinal chemistry for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting central nervous system and other therapeutic areas. It is primarily sought after by research institutions, custom synthesis firms, and pharmaceutical manufacturers engaged in the development of new drug candidates.

Application

• Pharmaceutical Intermediate: A critical chiral building block for the research and development of new drug molecules.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes.
• Custom Synthesis: Serves as a starting material or intermediate for contract research organizations (CROs) and CDMOs.
• API Synthesis: Incorporated into synthetic routes for potential Active Pharmaceutical Ingredients, especially those containing benzotriazole and pyrrolidine motifs.
• Chemical Biology Probes: Can be utilized in the development of chemical probes for studying biological pathways and target validation.

Basic Information

Product Name	(3S,5R,7Ar)-5-(Benzotriazol-1-Yl)-3-Phenyl[2,1-B]Oxazolopyrrolidine
CAS No.	205442-89-3
Molecular Formula	C20H16N4O
Molecular Weight	328.37 g/mol
Synonyms	5-(1H-Benzotriazol-1-yl)-3-phenyl-3a,4,5,6-tetrahydro-3H,7H-pyrrolo[2,1-b]oxazole; (3S,5R,7aR)-5-(1H-1,2,3-Benzotriazol-1-yl)-3-phenylhexahydropyrrolo[2,1-b][1,3]oxazole; 3-Phenyl-5-(1H-benzotriazol-1-yl)hexahydropyrrolo[2,1-b][1,3]oxazole; Benzotriazolyl Oxazolopyrrolidine Derivative; Fused Oxazole-Pyrrolidine Intermediate
EINECS	Contact for details

Quality Control

Our (3S,5R,7Ar)-5-(Benzotriazol-1-Yl)-3-Phenyl[2,1-B]Oxazolopyrrolidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification and impurity profiling via HPLC, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and chiral excess is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept sealed in a dry environment to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.