Description

2-Chloroquinoline-6-Sulfonyl Chloride is a versatile and highly reactive bifunctional organic intermediate. Its molecular structure, featuring both a chloroquinoline moiety and a sulfonyl chloride group, makes it a critical building block for the synthesis of complex molecules. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly in the development of kinase inhibitors, antimicrobial agents, and other biologically active heterocyclic compounds.
• Agrochemical Synthesis: Used to construct advanced fungicides, herbicides, and pesticides, leveraging the quinoline scaffold for enhanced bioactivity.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of specialized polymers and functional materials.
• Dye and Pigment Manufacturing: Acts as an intermediate for producing quinoline-based dyes and colorants with specific light-fastness properties.
• Chemical Biology Probes: Utilized in the creation of sulfonamide-based probes and labels for studying enzyme activity and protein interactions.
• Custom Synthesis & Contract Manufacturing: An essential raw material for custom synthesis houses serving the life sciences industry.

Basic Information

Product Name	2-Chloroquinoline-6-Sulfonyl Chloride
CAS No.	205055-71-6
Molecular Formula	C9H5Cl2NO2S
Molecular Weight	278.11 g/mol
Synonyms	6-(Chlorosulfonyl)-2-chloroquinoline; 2-Chloro-6-quinolinesulfonyl chloride; Quinoline-6-sulfonyl chloride, 2-chloro-; 2-Chloroquinoline-6-sulfonylchloride; 2-Chloro-6-sulfonylchloride quinoline; 205055-71-6; 2-Cl-6-SO2Cl-Quinoline
EINECS	Contact for details

Quality Control

Every batch of 2-Chloroquinoline-6-Sulfonyl Chloride is manufactured under strict quality management systems. We employ advanced analytical techniques including HPLC, GC, and NMR to ensure identity, purity, and consistency meet the exacting standards required for research and production. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) in a desiccated environment to prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.