Description

5-Nitroquinoline-8-Carbonitrile is a high-purity, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. Its unique molecular architecture, featuring both electron-withdrawing nitro and cyano substituents, makes it a critical precursor for constructing complex pharmacophores and functional materials. This compound is primarily sought by research and development teams in the pharmaceutical, agrochemical, and specialty chemical industries for applications in medicinal chemistry, material science, and as a key intermediate in multi-step synthetic routes.

Application

• Pharmaceutical Intermediate: Serves as a versatile scaffold for the synthesis of novel drug candidates, particularly in developing quinoline-based therapeutics with potential biological activity.
• Agrochemical Research: Used in the development of new active ingredients for crop protection products, leveraging its heterocyclic core for bioactivity.
• Material Science Precursor: Acts as a building block for creating advanced organic materials, such as ligands for metal-organic frameworks (MOFs) or components for electronic materials.
• Chemical Synthesis: Employed in academic and industrial R&D for complex organic transformations, including cross-coupling reactions and cyclization processes.
• Dye & Pigment Intermediate: Utilized in the synthesis of specialized dyes and pigments due to the chromophoric quinoline structure and substitutable functional groups.

Basic Information

Product Name	5-Nitroquinoline-8-Carbonitrile
CAS No.	205046-59-9
Molecular Formula	C10H5N3O2
Molecular Weight	199.17 g/mol
Synonyms	8-Cyano-5-nitroquinoline; Quinoline-8-carbonitrile, 5-nitro-; 5-Nitro-8-cyanoquinoline; 5-Nitroquinoline-8-carbonitrile; 205046-59-9
EINECS	Contact for details

Quality Control

Our 5-Nitroquinoline-8-Carbonitrile is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical data, including HPLC purity, identity confirmation (IR, NMR), and residual solvent analysis. A Certificate of Analysis (COA) is supplied with each batch, detailing all relevant specifications. Our quality management system supports compliance with cGMP and ISO standards for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed in a dry environment to minimize moisture exposure.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.