Description

2-Cyclohexen-1-One, 3-Hydroxy-2-[[8-(Methylsulfonyl)-5-Quinolinyl]Carbonyl]- is a high-purity, advanced pharmaceutical intermediate characterized by its complex bicyclic structure. This compound is of significant commercial importance for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular scaffolds. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of new chemical entities and complex organic syntheses.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the multi-step synthesis of proprietary drug candidates and investigational new drugs.
• Organic Synthesis Building Block: Used in research-scale and process chemistry for constructing complex quinoline and cyclohexenone-based molecular architectures.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies and lead optimization programs to develop new therapeutic agents.
• Contract Manufacturing (CMO): Supplied to contract development and manufacturing organizations (CDMOs) for cGMP production of clinical trial materials.
• Academic & Industrial R&D: Utilized in chemical research laboratories for exploring new synthetic methodologies and heterocyclic chemistry.

Basic Information

Product Name	2-Cyclohexen-1-One, 3-Hydroxy-2-[[8-(Methylsulfonyl)-5-Quinolinyl]Carbonyl]-
CAS No.	205045-95-0
Molecular Formula	C₁₇H₁₅NO₅S
Molecular Weight	345.37 g/mol
Synonyms	3-Hydroxy-2-[(8-methylsulfonyl-5-quinolinyl)carbonyl]-2-cyclohexen-1-one; 2-Cyclohexen-1-one, 3-hydroxy-2-((8-(methylsulfonyl)-5-quinolyl)carbonyl)-; 3-Hydroxy-2-(8-methanesulfonylquinoline-5-carbonyl)cyclohex-2-enone; 205045-95-0; 8-Methylsulfonyl-5-quinolinecarboxylic acid 3-hydroxy-2-oxo-1-cyclohexen-2-yl ester; Quinoline-5-carboxylic acid, 8-(methylsulfonyl)-, 2-(3-hydroxy-2-oxo-1-cyclohexen-1-yl) ester
EINECS	Contact for details

Quality Control

Our 2-Cyclohexen-1-One, 3-Hydroxy-2-[[8-(Methylsulfonyl)-5-Quinolinyl]Carbonyl]- is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for pharmaceutical research and development. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting purity, related substances, and other critical parameters.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed in a dry environment and away from direct light exposure to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.